Frontal fibrosing alopecia: A multicenter review of 355 patients

Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia

“…Thinning or total loss of the eyebrows was reported in 50-95% of the FFA cases (6,12,13,15). Vona et al stated that eyebrow loss is present in moderate-severe cases (14). In our study, total eyebrow loss was seen in 57% of the cases (8 cases), and others had partial eyebrow involvement.…”

“…FFA is disease of postmenopausal women by 95%, and the mean onset age of the disease is 67 (45-82) (2,3,4). A multi-center study performed by Vano et al, is the study including the largest series with 355 patients on this subject (14). In this study, investigators reported 12 male patients and 40 premenopausal women.…”

“…Eyelash loss in FFA is occasional and may indicate poor prognosis. Investigators reported that these cases require systemic treatment (14,20,23). In some studies, eyelash loss was detected in 3-26% of the cases (12,13).…”

“…Laboratory tests do not provide the desired assistance in diagnosis (3). Solely, ANA positivity was reported in some cases (14). As a possible autoimmune mechanism plays a role in the pathogenesis, FFA was reported to have the possibility of co-existing with other autoimmune diseases (14).…”

“…Case reports and series were reported in local and foreign literature (10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Here, we aimed to present the demographic, clinical and laboratory characteristics of female patients diagnosed and followed-up with FFA in our clinic by comparing these with the literature data.…”