Frontal bone defect repair with experimental glass‐fiber‐reinforced composite with bioactive glass granule coating

Tuusa, Sari; Peltola, Matti; Tirri, Teemu; Lassila, Lippo; Vallittu, Pekka K.

doi:10.1002/jbm.b.30716

Cited by 62 publications

(38 citation statements)

References 89 publications

(91 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As biomaterials they are utillized in several fields in dentistry [7][8][9]. FRCs have recently been tested as artificial bone material in head and neck surgery as well as in orthopaedics with encouraging results [10][11][12][13][14][15][16]. Wood has structural similarities to FRCs and bone.…”

Section: Introductionmentioning

confidence: 99%

The effect of heat treatment of wood on osteoconductivity

et al. 2009

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

The effect of heat treatment of wood on osteoconductivity

et al. 2009

View full text Add to dashboard Cite

“…The available options to reconstruct the frontal bone include autogenous bone graft (particularly split-thickness calvarial bone grafts) [7], alloplastic materials (e.g. titanium mesh, hydroxyapatite cement, and prefabricated custom acrylic implants) [8] and the bioactive glass-coated fiberreinforced composite (long-term studies are needed for use in humans) [9]. Methylmethacrylate is cheap, readily available and easy to use alloplastic material and remains the material of choice for cranioplasty [1,10].…”

Section: Discussionmentioning

confidence: 99%

Split Calvarial Graft to Repair the Large Frontal Bone Defect

Agrawal

Baisakhiya

Bhola³

2010

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

The ideal reconstructive material for cranioplasty is autogenous bone, however if it is not available the use of alloplastic materials is recommended. We present a case of 26-year-male patient who sustained compound depressed fracture of the frontal bone and associated anterior cranial fossa fracture following a road traffic accident. He was managed at hospital where the fractured bone fragments were removed but recently presented with watery discharge from nose (CSF rhinorrhoea) and cosmetic deformity of forehead. We describe the utilization of autogenous local frontal bone split calvarial graft for the reconstruction of the defect.

show abstract

“…More importantly, phosphate BGs can be drawn to fibers conveniently by conventional melt-spinning method [12]. Phosphate glass fibers (PGF) have been used as fillers for improving the mechanical properties and bioactivity of biomedical composites [13,14]. However, the lack of interconnected structures in filler-containing composites limits cell and tissue ingrowth.…”

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of fibrous chitosan-glued phosphate glass fiber scaffolds for bone regeneration

Zheng

Wei

et al. 2015

J Mater Sci: Mater Med

View full text Add to dashboard Cite

Phosphate glass fibers (PGF) have emerged as promising building blocks for constructing bone scaffolds. In this study, fibrous scaffolds (PGFS) were fabricated using a facile binding method at room temperature. PGFS exhibited an extracellular matrix-like morphology and were composed of PGF as matrix and chitosan as the natural binding glue. They showed an interconnected porous structure with a porosity of ~87% and pore size of 100-500 µm. PGFS exhibited the typical compressive stress-strain behaviour of highly porous, low-density, open-cell scaffolds. Their yield stress and modulus were ~0.38 and ~2.84 MPa, respectively, with the strength being higher than the lower bound of the compressive strength of cancellous bone. PGFS were degradable and the weight loss was about 25% after immersion in stimulated body fluid (SBF) for 28 days. In addition, the yield stress and the modulus decreased with increasing immersion time in SBF. Apatite formation could be detected on the surface of PGFS within 7 days of immersion in SBF. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay indicated that PGFS were non-cytotoxic against bone marrow stromal cells (bMSCs) after culture for up to 72 h. These results suggest that PGFS could be promising scaffolds for bone regeneration applications.

show abstract

Frontal bone defect repair with experimental glass‐fiber‐reinforced composite with bioactive glass granule coating

Abstract: This study suggests that the tested FRC implant with bioactive glass coating provides an alternative for bone defect reconstruction. However, more research on this composite material and its biocompatibility is needed.

Cited by 62 publications

References 89 publications

The effect of heat treatment of wood on osteoconductivity

The effect of heat treatment of wood on osteoconductivity

Split Calvarial Graft to Repair the Large Frontal Bone Defect

Preparation and characterization of fibrous chitosan-glued phosphate glass fiber scaffolds for bone regeneration

Contact Info

Product

Resources

About