Front Cover: The Effect of Visible Light on the Catalytic Activity of PLP‐Dependent Enzymes (ChemCatChem 10/2021)

Abstract

The Front Cover indicates the effect that especially blue light exposure, but also ordinary laboratory or sunlight can have on the activity of PLP‐dependent enzymes. In their Full Paper, T. Gerlach et al. show that most of the PLP‐dependent enzymes tested showed a significant loss of activity upon illumination. Consequently, by carrying out the enzyme production and reaction in the dark, and in particular by preserving the cofactor PLP from illumination, the catalytic activity could be increased immensely, in one case up to tenfold. That the effect of light varies with the choice of PLP‐dependent enzyme was demonstrated by the fact that one enzyme was completely resistant to any type of illumination.More information can be found in the Full Paper by T. Gerlach et al.