Front Cover: Serum Small Extracellular Vesicles Proteome of Tuberculosis Patients Demonstrated Deregulated Immune Response

Abstract

Quantitative proteome analysis of serum small extracellular vesicles isolated from healthy controls and drug naive active tuberculosis patients showed altered protein composition. A set of four important proteins (SERPINA1, KYAT3, HP and APOC3) showed deregulation. These important proteins are involved in neutralizing bacterial infection, psychotic symptoms, acute immune response and adipose tissue lipolysis. This is reported by Rakesh Arya, Deepti Dabral, Hossain Md. Faruquee, Himangshu Mazumdar, Saurav Jyoti Patgiri, Trinayan Deka, Rumi Basumatary, Rukuwe‐u Kupa, Chayale Semy, Wetetsho Kapfo, Kevideme Liegise, Inderjeet Kaur, Tenzin Choedon, Purnima Kumar, Rajendra Kumar Behera, Pranjal Deori, Reema Nath, Kerekha Khalo, Lahari Saikia, Vinotsole Khamo, Ranjan Kumar Nanda in article 1900062.