Front Cover Picture: Regioselective [2+2+2] Cycloaddition Reaction Using Allene‐ynes with Simple Allenes under Nickel Catalysis (Adv. Synth. Catal. 21/2019)

Abstract

The front cover picture, provided by Shigeru Arai and co‐workers, illustrates new protocols for the [2+2+2] cycloaddition reaction between allene‐ynes and simple allenes to create highly functionalized nitrogen heterocycles. DFT calculations play a key role to design new reaction pathways and control regio‐, site‐ and stereoselectivities of the cycloadducts. Details of this work can be found in the Communication on pages 4882–4887 (S. Arai, A. Izaki, Y. Amako, M. Nakajima, M. Uchiyama, A. Nishida, Adv. Synth. Catal. 2019, 361, 4882–4887; DOI: 10.1002/adsc.201900719).