Front Cover: Late‐Stage Functionalisation of Pyridine‐Containing Bioactive Molecules: Recent Strategies and Perspectives (Eur. J. Org. Chem. 16/2023)

Abstract

The Front Cover Cover illustrates how the pyridine ring of the antihistamine loratadine can be selectively functionalised at the ortho‐, meta‐, or para‐position (each of them activated by a thunder). Indeed, the selective functionalisation of this N‐heterocycle is often problematic, thus a lighthouse guides the chemists through the late‐stage functionalisations of pyridine‐containing biomolecules. More information can be found in the Review by V. Fasano et al.