Front Cover: Construction of a Triangle‐Shaped Trimer and a Tetrahedron Using an α‐Helix‐Inserted Circular Permutant of Cytochrome c555 (Chem. Asian J. 10/2018)
Abstract:A building block protein BBP is designed by circularly permutating thermostable cytochrome c555 (pictured as pink and green pieces on the front cover) and connecting the original N‐ and C‐terminal α‐helices with an α‐helical linker (blue piece). The N‐terminal α‐helix of one BBP molecule interacts intermolecularly with the C‐terminal α‐helix of another BBP molecule in a defined angle, resulting in the formation of a triangle‐shaped trimer and a tetrahedron by four of these trimers. This approach of combining c… Show more
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