Front Cover: 1‐Hydrosilatrane: A Locomotive for Efficient Ketone Reductions (Eur. J. Org. Chem. 2/2017)

Abstract

The cover picture shows artist Jesse Mai's imagination of the reduction of ketones to alcohols by 1‐hydrosilatrane. The accompanying work describes this mild method for reduction, which makes use of a cheap, safe, easy‐to‐handle, and environmentally friendly silane reducing reagent. The reported results include the conversion of a wide scope of ketones to alcohols, as well as demonstrations of stereoselective reductions: the diastereoselective reduction of (–)‐menthone to (+)‐neomenthol and the reduction of a prochiral ketone to an alcohol with an enantiomeric ratio of 87:13. Details are discussed in the Communication by M. J. Adler et al. on page 229 ff (DOI: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201601256/abstract).