Abstract. This paper presents a usability study for text entry with a new version of the assistive keyboard replacement OnScreenDualScribe. Over five sessions (approximately 1 hr/session), three able-bodied novice participants achieved an entry rate of 13.9 wpm. In a case study, one disabled expert achieved an entry rate of 6.6 wpm. The main aspects of the software are described and differences to the ancestor DualScribe are highlighted. Finally, the potential impact of the system for persons with neuromuscular diseases -a user group it particularly accommodates -is elaborated.