“…Severe PED outbreaks have recurred almost simultaneously in many Asian countries, such as the Philippines, Vietnam, Thailand, South Korea and Japan, and US prototype-like GII PEDV strains have been found to be accountable for these outbreaks (Cheun-Arom et al, 2016;Chung et al, 2016;Lee et al, 2017;Lin et al, 2014;Paraguison-Alili and Domingo, 2016;Van Diep et al, 2015). In addition, the US S INDEL-like strains have been described in many European countries, such as Belgium, France, Germany, Italy, Portugal, Slovenia and Netherlands (Choudhury et al, 2016;Pensaert and Martelli, 2016;Stadler et al, 2015). Therefore, PEDV has currently re-emerged as one of the most devastating viral diseases of swine in the world, resulting in tremendous economic losses to the global pig industry.…”