From the Blood-Brain Barrier to Childhood Development: A Case of Acute-Onset Psychosis and Cognitive Impairment Attributed to Systemic Lupus Erythematosus in an Adolescent Female

Abstract

Learning objectives: After participating in this CME activity, the clinician will be better able to:• Interpret classifications of neuropsychiatric systemic lupus erythematosus (NPSLE).• Identify determining factors of neuropsychiatric events.• Analyze current evidence regarding disease pathways for NPSLE.

Introduction

“…Finally, the themes reviewed in this special issue are put into practice through evaluation of a complex clinical case, “From the Blood-Brain Barrier to Childhood Development: A Case of Acute-Onset Psychosis and Cognitive Impairment Attributed to Systemic Lupus Erythematosus in an Adolescent Female,” described by Johnson and colleagues 11 . This case involves an adolescent female patient who presented with subacute onset of cognitive and psychotic symptoms on a background of neurodevelopmental delays that resolved over time.…”