Abstract:BackgroundIn 30 years of experience in responding to the HIV epidemic, critical decisions and program characteristics for successful scale-up have been studied. Now leaders face a new challenge: sustaining large-scale HIV prevention programs. Implementers, funders, and the communities served need to assess what strategies and practices of scaling up are also relevant for sustaining delivery at scale.MethodsWe reviewed white and gray literature to identify domains central to scaling-up programs and reviewed HIV… Show more
“…The literature on health program sustainability has referred to this distinction as one between the core components and the customizable components of interventions [15–17, 23]. Hirschhorn et al [13] have called for an appropriate balance between adaptation and flexibility in the scale-up of HIV interventions [46]. In contrast with a previous study [45], we found that most modifications to ART were made at the organization level as opposed to individual clinicians.…”
Section: Discussioncontrasting
confidence: 68%
“…Devising service delivery models that are suited to resource-limited contexts is acknowledged as an important strategy for fostering the sustainability of ART scale-up programs in SSA [10, 11]. Service delivery design alternatives to the traditional model of physician-centered, clinic-based care are becoming critical in SSA [4, 12, 13]. Sustaining and expanding ART coverage in resource-limited settings requires modifications and adaptations of ART delivery models to meet the continually rising demand [10, 11].…”
BackgroundIn November 2015, WHO released new treatment guidelines recommending that all diagnosed as HIV positive be enrolled on antiretroviral therapy (ART). Sustaining and expanding ART scale-up programs in resource-limited settings will require adaptations and modifications to traditional ART delivery models to meet the rapid increase in demand. We identify modifications to ART service delivery models by health facilities in Uganda to sustain ART interventions over a 10-year period (2004–2014).MethodsA mixed methods approach involving two study phases was adopted. In the first phase, a survey of a nationally representative sample of health facilities (n = 195) in Uganda which were accredited to provide ART between 2004 and 2009 was conducted. The second phase involved semi-structured interviews (n = 18) with ART clinic managers of 6 of the 195 health facilities purposively selected from the first study phase. We adopted a thematic framework consisting of four categories of modifications (format, setting, personnel, and population).ResultsThe majority of health facilities 185 (95%) reported making modifications to ART interventions between 2004 and 2014. Of the 195 health facilities, 157 (81%) rated the modifications made to ART as “major.” Modifications to ART were reported under all the four themes. The quantitative and qualitative findings are integrated and presented under four themes. Format: Reducing the frequency of clinic appointments and pharmacy-only refill programs was identified as important strategies for decongesting ART clinics. Setting: Home-based care programs were introduced to reduce provider ART delivery costs. Personnel: Task shifting to non-physician cadre was reported in 181 (93%) of the health facilities. Population: Visits to the ART clinic were rationalized in favor of the sub-population deemed to have more clinical need. Two health facilities focused on patients living nearer the health facilities to align with targets set by external donors.ConclusionsOver the study period, health facilities made several modifications ART interventions to improve fit with their resource-constrained settings thereby promoting long-term sustainability. Further research evaluating the effect of these modifications on patient outcomes and ART delivery costs is recommended. Our findings have implications for the sustainability of ART scale-up programs in Uganda and other resource-limited settings.
“…The literature on health program sustainability has referred to this distinction as one between the core components and the customizable components of interventions [15–17, 23]. Hirschhorn et al [13] have called for an appropriate balance between adaptation and flexibility in the scale-up of HIV interventions [46]. In contrast with a previous study [45], we found that most modifications to ART were made at the organization level as opposed to individual clinicians.…”
Section: Discussioncontrasting
confidence: 68%
“…Devising service delivery models that are suited to resource-limited contexts is acknowledged as an important strategy for fostering the sustainability of ART scale-up programs in SSA [10, 11]. Service delivery design alternatives to the traditional model of physician-centered, clinic-based care are becoming critical in SSA [4, 12, 13]. Sustaining and expanding ART coverage in resource-limited settings requires modifications and adaptations of ART delivery models to meet the continually rising demand [10, 11].…”
BackgroundIn November 2015, WHO released new treatment guidelines recommending that all diagnosed as HIV positive be enrolled on antiretroviral therapy (ART). Sustaining and expanding ART scale-up programs in resource-limited settings will require adaptations and modifications to traditional ART delivery models to meet the rapid increase in demand. We identify modifications to ART service delivery models by health facilities in Uganda to sustain ART interventions over a 10-year period (2004–2014).MethodsA mixed methods approach involving two study phases was adopted. In the first phase, a survey of a nationally representative sample of health facilities (n = 195) in Uganda which were accredited to provide ART between 2004 and 2009 was conducted. The second phase involved semi-structured interviews (n = 18) with ART clinic managers of 6 of the 195 health facilities purposively selected from the first study phase. We adopted a thematic framework consisting of four categories of modifications (format, setting, personnel, and population).ResultsThe majority of health facilities 185 (95%) reported making modifications to ART interventions between 2004 and 2014. Of the 195 health facilities, 157 (81%) rated the modifications made to ART as “major.” Modifications to ART were reported under all the four themes. The quantitative and qualitative findings are integrated and presented under four themes. Format: Reducing the frequency of clinic appointments and pharmacy-only refill programs was identified as important strategies for decongesting ART clinics. Setting: Home-based care programs were introduced to reduce provider ART delivery costs. Personnel: Task shifting to non-physician cadre was reported in 181 (93%) of the health facilities. Population: Visits to the ART clinic were rationalized in favor of the sub-population deemed to have more clinical need. Two health facilities focused on patients living nearer the health facilities to align with targets set by external donors.ConclusionsOver the study period, health facilities made several modifications ART interventions to improve fit with their resource-constrained settings thereby promoting long-term sustainability. Further research evaluating the effect of these modifications on patient outcomes and ART delivery costs is recommended. Our findings have implications for the sustainability of ART scale-up programs in Uganda and other resource-limited settings.
“…They related to cost-effectiveness, equity, harms, ethics, bottom-up/top-down scaling-up, and the context in which the EBI was scaled up (see Figure 2). To discuss them, we identified 45 scaling-up studies that raised these difficulties, of which 13 were on costeffectiveness estimates or cost-analysis models [22][23][24][25][26][27][28][29][30][31][32][33][34], 14 on equity [35][36][37][38][39][40][41][42][43][44][45][46][47][48], four on harms [16,[49][50][51][52], three on ethics [53][54][55], six on top-down implementation [42,[56][57][58][59][60], and eight on contextual problems [40,43,[61][62][63][64]…”
Section: Introductionmentioning
confidence: 99%
“…The health inequities pitfall: some people will necessarily be left out Many studies highlight equity as a motive for scalingup effective healthcare interventions: an EBI that is delivered only to a small population constitutes a health inequity, as others are deprived of its proven health benefits [36,[38][39][40]42,43,[46][47][48].…”
Policy-makers worldwide are increasingly interested in scaling up evidence-based interventions (EBIs) to larger populations, and implementation scientists are developing frameworks and methodologies for achieving this. But scaling-up does not always produce the desired results. Why not? We aimed to enhance awareness of the various pitfalls to be anticipated when planning scale-up. In lower-and middle-income countries (LMICs), the scale-up of health programs to prevent or respond to outbreaks of communicable diseases has been occurring for many decades. In high-income countries, there is new interest in the scaling up of interventions that address communicable and non-communicable diseases alike. We scanned the literature worldwide on problems encountered when implementing scale-up plans revealed a number of potential pitfalls that we discuss in this paper. We identified and discussed the following six major pitfalls of scaling-up EBIs: 1) the cost-effectiveness estimation pitfall, i.e. accurate cost-effectiveness estimates about real-world implementation are almost impossible, making predictions of economies of scale unreliable; 2) the health inequities pitfall, i.e. some people will necessarily be left out and therefore not benefit from the scaled-up EBIs; 3) the scaled-up harm pitfall, i.e. the harms as well as the benefits may be amplified by the scaling-up; 4) the ethical pitfall, i.e. informed consent may be a challenge on a grander scale; 5) the top-down pitfall, i.e. the needs, preferences and culture of end-users may be forgotten when scale-up is directed from above; and 6) the contextual pitfall, i.e. it may not be possible to adapt the EBIs to every context. If its pitfalls are addressed head on, scaling-up may be a powerful process for translating research data into practical improvements in healthcare in both LMICs and high-income countries, ensuring that more people benefit from EBIs.
“…Research focused on the transmission of communicable diseases, and the influence that globalisation has on the spread of these [34, 35]. Most papers were in relation to HIV and AIDS, and included HIV programme sustainability, access to interventions and adherence to treatments [17, 36, 37]. Sustained use and access to antiretroviral therapy was another frequently occurring topic under this construct.…”
Founded in 2005, Globalization and Health was the first open access global health journal. The journal has since expanded the field, and its influence, with the number of downloaded papers rising 17-fold, to over 4 million. Its ground-breaking papers, leading authors -including a Nobel Prize winner-and an impact factor of 2.25 place it among the top global health journals in the world. To mark the ten years since the journal's founding, we, members of the current editorial board, undertook a review of the journal's progress over the last decade. Through the application of an inductive thematic analysis, we systematically identified themes of research published in the journal from 2005 to 2014. We identify key areas the journal has promoted and consider these in the context of an existing framework, identify current gaps in global health research and highlight areas we, as a journal, would like to see strengthened.
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