“…It has been proposed that Cuba's low rate of HIV infection is due to several factors that served to prevent sexual transmission of the virus, including: wide-scale HIV screening and subsequent contact tracing of HIV-positive individuals, mandatory quarantine of the first HIV-infected individuals at sanatoria, free access to a well structured public health system, comprehensive HIV education campaigns, coordinated work of Cuban government agencies and community, and restricted tourism between Cuba and western countries up to the early 1990s [43], [44], [45], [46]. The estimated initial growth rates of the major HIV-1 Cuban clades (∼0.4–1.6 year −1 ), however, were comparable to those obtained for different HIV-1 epidemics in the Americas (∼0.5–1.3 year −1 ) [38], [47], [48], [49], [50], [51], [52], Europe (∼0.4–1.5 year −1 ) [52], [53], [54], [55], Africa (∼0.2–0.8 year −1 ) [47], [52], [56], [57], [58] and Asia (∼0.8 year −1 ) [59].…”