From Prediction Tools to Precision Medicine in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are multiorgan autoimmune disorders resulting in irreversible organ damage. Left untreated, AAVs are fatal, and aggressive immunosuppressive treatment has transformed them into chronic relapsing conditions.