Market integration (MI) is a complex process through which individuals transition from relatively subsistence-based to market-oriented activities. Changes associated with MI alter the landscapes of individual health and reproductive decision-making. While the consequences of MI are often easily detected, the specific pathways through which MI affects decision-making are context-dependent and under-investigated. We employed an information-theoretic model selection approach to characterize relationships between multiple indicators of MI and three outcomes commonly associated with MI, waist circumference (n = 431), systolic blood pressure (n = 472), and age at first reproduction (n = 974), among adult matrilineal Mosuo participants from 505 households in six villages in southwest China. Different MI indicators, distributed across individual, household, and community levels of social organization, predicted these three outcomes, demonstrating that individuals’ personal circumstances, household structure, and community affect how they experience and respond to MI. We emphasize the importance of identifying and measuring multiple context-appropriate indicators of MI across levels of social organization. Theoretical frameworks that situate hypotheses of MI within specific social, cultural, and historical contexts will be most capable of identifying specific pathways through which multiple elements of MI affect different domains of decision making.