From Neurons to Social Beings: Short Review of the Mirror Neuron System Research and Its Socio-Psychological and Psychiatric Implications

Jeon, Hong Jun; Lee, Seung Hwan

doi:10.9758/cpn.2018.16.1.18

Cited by 65 publications

(48 citation statements)

References 151 publications

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“…According to the Singapore Mental Health Study [6], the prevalence of SI among those with lifetime MDD was 43.6%, wherein approximately 31.5% and 28.2% of individuals planned and attempted suicide respectively. MDD has been known as a social and neuronal mental illness representing a complex mechanism of mental activity [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Frontal Alpha Asymmetry Moderated by Suicidal Ideation in Patients with Major Depressive Disorder: A Comparison with Healthy Individuals

Roh

Kim

et al. 2020

Clin Psychopharmacol Neurosci

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Objective: Frontal alpha asymmetry (FAA) of electroencephalography (EEG) has been studied to differentiate patients with major depressive disorder (MDD) from healthy controls (HC). However, inconsistent results have been obtained thus far. Suicidal ideation (SI) has been known to alter frontal lobe activity, and could be an important covariate in FAA studies. This study aimed to explore the influence of FAA on the relationship among MDD patients with SI and without SI, and HC. Methods: Sixty-seven patients with MDD (44 without and 23 with SI) and 60 HCs were recruited. Resting state EEG was recorded with their eyes open, and FAA as a lateralized index of alpha power was calculated in the frontal brain region. Hamilton Rating Scale for Anxiety and Depression scores were estimated. Results: FAA was higher (increased alpha power in the left frontal region) in the MDD group than in the HC group. The FAA was lower (reduced alpha power in the left frontal region) in MDD patients with SI than in MDD patients without SI. The severity of depression and anxiety symptoms were significantly correlated with FAA only in MDD patients with SI. SI moderated the effects of depressive symptom on FAA in the MDD group. Conclusion: Our results suggest that SI is a clinically important moderator of frontal alpha asymmetry in patients with MDD.

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Section: Introductionmentioning

confidence: 99%

Frontal Alpha Asymmetry Moderated by Suicidal Ideation in Patients with Major Depressive Disorder: A Comparison with Healthy Individuals

Roh

Kim

et al. 2020

Clin Psychopharmacol Neurosci

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“…The human brain contains a distinct class of neurons called the mirror neuron system (MNS), which discharge both when individuals perform an action, and when they observe another person performing an action with a similar intention ( Lago-Rodriguez et al, 2013 ). It is generally accepted that the MNS plays functional roles in intention understanding ( Bonini et al, 2010 ; Cacioppo et al, 2017 ), emotion recognition and empathy ( Molnar-Szakacs et al, 2009 ; Goodarzi et al, 2015 ), action imitation ( Molenberghs et al, 2009 ; Reynolds et al, 2015 ), self-recognition ( Jeon and Lee, 2018 ) and the evolution of language ( Zarr et al, 2013 ). The MNS transforms sensory information describing the actions of others into a motor representation, which is similar to the representation internally generated by an observer when they actually perform or imagine the action.…”

Section: Introductionmentioning

confidence: 99%

Neural Basis of Action Observation and Understanding From First- and Third-Person Perspectives: An fMRI Study

Liu

Lin

et al. 2018

Front. Behav. Neurosci.

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Understanding the intentions of others while observing their actions is a fundamental aspect of social behavior. However, the differences in neural and functional mechanisms between observing actions from the first-person perspective (1PP) and third-person perspective (3PP) are poorly understood. The present study had two aims: (1) to delineate the neural basis of action observation and understanding from the 1PP and 3PP; and (2) to identify whether there are different activation patterns during action observation and understanding from 1PP and 3PP. We used a blocked functional magnetic resonance imaging (fMRI) experimental design. Twenty-six right-handed participants observed interactions between the right hand and a cup from 1PP and 3PP. The results indicated that both 1PP and 3PP were associated with similar patterns of activation in key areas of the mirror neuron system underlying action observation and understanding. Importantly, besides of the core network of mirror neuron system, we also found that parts of the basal ganglia and limbic system were involved in action observation in both the 1PP and 3PP tasks, including the putamen, insula and hippocampus, providing a more complete understanding of the neural basis for action observation and understanding. Moreover, compared with the 3PP, the 1PP task caused more extensive and stronger activation. In contrast, the opposite comparison revealed that no regions exhibited significantly more activation in the 3PP compared with the 1PP condition. The current results have important implications for understanding the role of the core network underlying the mirror neuron system, as well as parts of the basal ganglia and limbic system, during action observation and understanding.

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“…Modern neuroscience, notably through the discovery of mirror neurons (for a review see Jeon and Lee, 2018 ), confirmed many of these early intuitions on empathy (Decety et al, 2012 ).…”

Section: Relationships Are Embodiedmentioning

confidence: 91%

Interpersonal Biofeedback in Psychodynamic Psychotherapy

2020

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From Neurons to Social Beings: Short Review of the Mirror Neuron System Research and Its Socio-Psychological and Psychiatric Implications

Cited by 65 publications

References 151 publications

Frontal Alpha Asymmetry Moderated by Suicidal Ideation in Patients with Major Depressive Disorder: A Comparison with Healthy Individuals

Frontal Alpha Asymmetry Moderated by Suicidal Ideation in Patients with Major Depressive Disorder: A Comparison with Healthy Individuals

Neural Basis of Action Observation and Understanding From First- and Third-Person Perspectives: An fMRI Study

Interpersonal Biofeedback in Psychodynamic Psychotherapy

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