2006
DOI: 10.1590/s0004-27302006000400011 View full text |Buy / Rent full text
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Abstract: Primary hyperparathyroidism often presents as an asymptomatic disorder. In our institution, routine serum calcium measurements have now been used as part of medical examination for 23 years. Out of 124 patients consecutively seen at our institution, 47% presented with no symptoms related to the disease, while 25% presented with severe skeletal involvement and osteitis fibrosa cystica, 25% with renal stone disease without overt bone involvement, and 2% with the typical neuropsychiatric syndrome. This same patte… Show more

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“…The main cause in 85%-90% of cases, is the presence of a solitary parathyroid adenoma (2,3). In the other affected patients, hyperplasia or multiple adenomas occur, the latter common in familial forms (3).…”
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“…The main cause in 85%-90% of cases, is the presence of a solitary parathyroid adenoma (2,3). In the other affected patients, hyperplasia or multiple adenomas occur, the latter common in familial forms (3).…”
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“…PHPT occurs most commonly in individuals over 50 years of age and in postmenopausal women, showing a prevalence of about 0.78% in patients evaluated in reference services (4). Although the clinical presentation is variable the asymptomatic hypercalcemia form, detected by routine screening, is the most common (50% to 80%) (2). However, the presentation is variable, with patients demonstrating a range from normocalcemia to severe hypercalcemic PHPT (1).…”
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“…A study of panoramic and periapical radiographs of 42 patients on haemodialysis and having renal osteodystrophy, demonstrated a progressive increase in periodontal disease, loss of lamina dura, deviation in the trabecular pattern, Brown tumor "pseudocyst" formation and pulp calcifications (Bandeira et al, 2006). Bandeira et al, tell the Brazilian experience of the severe and soft primary hyperparathyroidism in Pernambuco-Brazil.…”
Section: Hyperparathyroidismmentioning
“…Clinicamente, os sintomas do hiperparatireoidismo primário diferem pouco quando este é esporádico ou de causa hereditária, podendo ser assintomático ou, em sua apresentação clássica, promover grave comprometimento ósseo e renal (5,21 A hipercalcemia no HFI é geralmente mais grave comparada às outras síndromes familiares que cursam com hiperparatireoidismo primário. O desenvolvimento da hipercalcemia também é mais precoce no HFI do que na apresentação esporádica, podendo ocorrer em faixas etárias semelhantes às das NEM, ou mesmo na infância e adolescência (23).…”
Section: Discussão E Conclusõesunclassified