“…m = 1, …, M, where F (m) represent the system/method degradation operators usually referred to as the imaging system point spread functions (PSF), and vectors n (m) represent composite noises (usually with unknown statistics) in the actually acquired images, respectively. Different RS imaging methods incorporate different definitions for corresponding employed objective (cost) functions {J m (v)} [2], [3], [5], [6], [8], [10]. For the deterministic constrained least squares (CLS) method [2], [3]…”