From Lung to Brain - Respiration Modulates Neural and Mental Activity

Goheen, Josh; Anderson, John A. E.; Zhang, Jianfeng; Northoff, Georg

doi:10.31234/osf.io/zyd8g

Cited by 2 publications

(1 citation statement)

References 64 publications

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“…Possible examples of allostasis are the respiration-entrained 0.16-Hz oscillations during low anxiety, the pacemaker-entrained 0.16 Hz oscillations, and the 0.32 Hz respiration oscillations during high anxiety 16,17 . The importance of respiration as integral rhythm of the brain's neural activity is highlighted in two recently published papers from Northoff 's group 51,52 . Respiration is less a confounder variable in fMRI data, but more an intrinsic part of the brain's entrainment and synchronization processes.…”

Section: Discussionmentioning

confidence: 99%

Respiration-entrained brain oscillations in healthy fMRI participants with high anxiety

Pfurtscheller

Kamiński

Blinowska

et al. 2023

Sci Rep

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Brain-body interactions can be studied by using directed coupling measurements of fMRI oscillations in the low (0.1–0.2 Hz) and high frequency bands (HF; 0.2–0.4 Hz). Recently, a preponderance of oscillations in the information flow between the brainstem and the prefrontal cortex at around 0.15/0.16 Hz was shown. The goal of this study was to investigate the information flow between BOLD-, respiratory-, and heart beat-to-beat interval (RRI) signals in the HF band in healthy subjects with high anxiety during fMRI examinations. A multivariate autoregressive model was concurrently applied to the BOLD signals from the middle frontal gyrus (MFG), precentral gyrus and the brainstem, as well as to respiratory and RRI signals. Causal coupling between all signals was determined using the Directed Transfer Function (DTF). We found a salience of fast respiratory waves with a period of 3.1 s (corresponding to ~ 0.32 Hz) and a highly significant (p < 0.001) top-down information-flow from BOLD oscillations in the MFG to the brainstem. Additionally, there was a significant (p < 0.01) information flow from RRI to respiratory oscillations. We speculate that brain oscillations around 0.32 Hz, triggered by nasal breathing, are projected downwards to the brainstem. Particularly interesting is the driving force of cardiac to respiratory waves with a ratio of 1:1 or 1:2. These results support the binary hierarchy model with preferred respiratory frequencies at 0.32 Hz and 0.16 Hz.

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Section: Discussionmentioning

confidence: 99%

Respiration-entrained brain oscillations in healthy fMRI participants with high anxiety

Pfurtscheller

Kamiński

Blinowska

et al. 2023

Sci Rep

View full text Add to dashboard Cite

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Prefrontal Cortex Activation during Diaphragmatic Breathing in Women with Fibromyalgia: An fNIRS Case Report

Kim,

Jung,

Lee

2023

Phys Ther Rehabil Sci

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Objective: The present study is designed to delve deeper into the realm of fibromyalgia (FM) symptom management by investigating the effects of diaphragmatic breathing on the prefrontal cortex (PFC) in women diagnosed with FM. Using functional near-infrared spectroscopy (fNIRS), the study aims to capture real-time PFC activation patterns during the practice of diaphragmatic breathing. The overarching objective is to identify and understand the underlying neural mechanisms that may contribute to the observed clinical benefits of this relaxation technique. Design: A case report Methods: To achieve this, a twofold approach was adopted: First, the patient's breathing patterns were meticulously examined to detect any aberrations. Following this, fNIRS was employed, focusing on the activation dynamics within the PFC. Results: Our examination unveiled a notable breathing pattern disorder inherent to the FM patient. More intriguingly, the fNIRS analysis offered compelling insights: the ventrolateral prefrontal cortex (VLPFC) displayed increased activation. In stark contrast, regions of the anterior prefrontal cortex (aPFC) and orbitofrontal cortex (OFC) manifested decreased activity, especially when benchmarked against typical activations seen in healthy adults. Conclusions: These findings, derived from a nuanced examination of FM, underscore the condition's multifaceted nature. They highlight the imperative to look beyond conventional symptomatology and appreciate the profound neurological and physiological intricacies that define FM.

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From Lung to Brain - Respiration Modulates Neural and Mental Activity

Cited by 2 publications

References 64 publications

Respiration-entrained brain oscillations in healthy fMRI participants with high anxiety

Respiration-entrained brain oscillations in healthy fMRI participants with high anxiety

Prefrontal Cortex Activation during Diaphragmatic Breathing in Women with Fibromyalgia: An fNIRS Case Report

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