From Innovation to Market: An Analysis of the Propolis Production Chain

Oliveira, Frederico Ivair Santiago de; Oki, Yumi; Resende, Fernando M.; Angrisano, Patrícia; Rosa, Dian Carlos Pinheiro; Arantes-Garcia, Lucas; Fernandes, Geraldo Wilson

doi:10.1007/978-3-030-83511-8_23

Cited by 5 publications

(4 citation statements)

References 31 publications

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“…The honeybee collects resin from the main budding buds of alecrim-do-campo and uses it to produce propolis in the hive (Righi et al, 2011;Zabaiou et al, 2017). Propolis, particularly the Green Propolis, not only helps to protect the hive but also has several benefits for human health (antibacterial, antifungal, anti-inflammatory, antitumor and immunostimulating properties, among others) due to its complex composition, making it a highly attractive product (Bankova et al, 2000;Chan et al, 2013;Oliveira et al, 2021;Silva-Beltrán et al, 2022). Alecrim-do-campo, in turn, can be used to recover areas of degraded vegetation, which benefits local biodiversity (Fernandes et al, 2016).…”

Section: Project Baccharismentioning

confidence: 99%

“…Despite some seasonal instability, producing propolis is potentially profitable (Mountford-McAuley et al, 2021). After the pandemic, prices in the international market increased substantially, with Japan being an important consumer (Oliveira et al, 2021). However, this Brazilian industry still has a high level of informality in the upstream and concentration of few players in the downstream (Wilkinson et al, 2017).…”

Section: Project Baccharismentioning

confidence: 99%

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The authentic Bee-Coin

2023

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This paper proposes an innovative financial instrument to fund projects that combine profit-making with significant social or environmental goals, specially in emerging or low-income economies. The proposal is based on improvements to the typical impact bond model with the aim of better aligning the parties' incentives, and also making it more transparent, traceable and compatible with revenue-generating projects. It is applied to a pilot project to fund the establishment of a robust supply chain of green propolis in Minas Gerais, Brazil. Propolis is a natural product with benefits for human health, which has been consumed by humans for decades and raised substantial global interest after the Covid-19 pandemic. This project addresses some industry issues (in terms of product quality and supply stability) and aims to provide biodiversity recovery, subsistence farming and resocialization through work. A financial model with stochastic variables is simulated, incorporating a reward system based on the impact outcomes. The results confirm that the instrument improves risk-return trade-off and advocate for its use in projects with sustainability objectives.

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Section: Project Baccharismentioning

confidence: 99%

Section: Project Baccharismentioning

confidence: 99%

The authentic Bee-Coin

2023

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“…De modo a identificar as patentes sobre as espécies de Baccharis, foi conduzida uma revisão sistemática utilizando o motor de busca de patentes Google Patents e a consulta de cinco bancos de dados internacionais e de acesso gratuito: dracunculifolia, com inúmeras atividades biológicas conhecidas (CHEN et al, 2019;ROJCZYK et al, 2020;FILHO et al, 2021;OLIVEIRA et al, 2022), portanto, trata-se de uma área de estudo completa o suficiente para representar uma área de interesse a parte, devido à vasta comprovação científica.…”

Section: Procedimentos De Seleção Das Patentesunclassified

Análise da prospecção tecnológica por meio de revisão sistemática seguida de meta análise das patentes do gênero Baccharis

Amancio,

Silva,

García

et al. 2023

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“…As the materials that bees use to produce propolis are collected by them from diverse botanical sources, the potential for contamination with pollutants varies depending on the region and specific plants involved [8]. Poplar propolis, for example, is susceptible to heavy metal accumulation and pesticide residues due to the characteristics of this type of tree and the environments where it grows [9].…”

Section: Introductionmentioning

confidence: 99%

Development and Characterization of High-Absorption Microencapsulated Organic Propolis EPP-AF® Extract (i-CAPs)

Berretta,

De Lima,

Falcão

et al. 2023

Molecules

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The demand for organic and functional food continues to increase yearly. Among the available functional foods, propolis is a bee product that has various beneficial properties, including antimicrobial, antioxidant, and anti-inflammatory activities. However, it generally is only available in ethanol solution, which has poor bioavailability, as it is relatively insoluble in water. The use of such ethanol extracts is often objectionable because of the alcohol content and because they have a strong and striking taste. Development of alternatives that can efficiently and safely increase solubility in water, and that meet organic production specifications, has been a challenge. To address these concerns, microcapsules were developed using spray-dryer technology from an emulsion based on EPP-AF® propolis and gum arabic (i-CAPS). These propolis-loaded microcapsules were characterized using FT-IR, SEM, TGA, HPLC, and spectrophotometric techniques, along with determination of antimicrobial, antioxidant, antitumor, anti-inflammatory, and antihypercholesterolemic activities, as well as permeability in in vitro models. The production system resulted in microcapsules with a spherical shape and an encapsulation efficiency of 93.7 ± 0.7%. They had IC50s of 2.654 ± 0.062 and 7.342 ± 0.058 µg/mL by FRAP and DPPH antioxidant methods, respectively. The EPP-AF® i-CAPS also had superior antimicrobial activity against Gram-positive bacteria. Antitumor activity was calculated based on the concentration that inhibited 50% of growth of AGS, Caco-2, and MCF-7 cell strains, giving results of 154.0 ± 1.0, 117 ± 1.0, and 271.0 ± 25 µg/mL, respectively. The microcapsule presentation reduced the permeation of cholesterol by 53.7%, demonstrating antihypercholesterolemic activity, and it improved the permeability of p-coumaric acid and artepillin C. The IC50 for NO production in RAW 264.7 cells was 59.0 ± 0.1 µg/mL. These findings demonstrate the potential of this new propolis product as a food and pharmaceutical ingredient, though additional studies are recommended to validate the safety of proposed dosages.

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From Innovation to Market: An Analysis of the Propolis Production Chain

Cited by 5 publications

References 31 publications

The authentic Bee-Coin

The authentic Bee-Coin

Análise da prospecção tecnológica por meio de revisão sistemática seguida de meta análise das patentes do gênero Baccharis

Development and Characterization of High-Absorption Microencapsulated Organic Propolis EPP-AF® Extract (i-CAPs)

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