With airborne transmissions found as one of the major transmission routes of SARS-CoV-2, its transmission in airliner cabin environments drew special attention due to high number of imported cases and in-cabin transmissions. This study numerically investigated the transmission of COVID-19 by cough-induced particles in a cabin section of Boeing 737 model. One passenger was coughing in each case, while cough particles with measured size distributions were released during coughs and were tracked using the Lagrangian framework. Outcomes revealed that cough flow released by passengers could develop rapidly into a strong turbulent cough jet, breaking up the local airflow field. The released cough particles were largely dominated by the cough jet within 5 s, especially the first 1.5 s. Deposition of particles under 100 µm were relatively delayed when released from a window-seat location. Small particles (under 50 µm) released by a window-seat passenger were more likely to spread widely in the studied cabin section, which could lead to the highest exposure risks to nearby passengers. Also, due to ventilation design and seating arrangement, cough particles released by the middle-seat passenger were found easily trapped in his/her own local environment. Cough particles released from aisle-seat passengers had the least exposure risk to adjacent passengers.