From Host Defense to Metabolic Signatures: Unveiling the Role of γδ T Cells in Bacterial Infections
Namya Nanda,
Martin P. Alphonse
Abstract:The growth of antibiotic-resistant bacterial infections necessitates focusing on host-derived immunotherapies. γδ T cells are an unconventional T cell subset, making up a relatively small portion of healthy circulating lymphocytes but a substantially increased proportion in mucosal and epithelial tissues. γδ T cells are activated and expanded in response to bacterial infection, having the capability to produce proinflammatory cytokines to recruit neutrophils and clear infection. They also play a significant ro… Show more
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