From dysbiosis to defense: harnessing the gut microbiome in HIV/SIV therapy
Jason M. Brenchley,
Sergio Serrano-Villar
Abstract:Background
Although the microbiota has been extensively associated with HIV pathogenesis, the majority of studies, particularly those using omics techniques, are largely correlative and serve primarily as a basis for hypothesis generation. Furthermore, most have focused on characterizing the taxonomic composition of the bacterial component, often overlooking other levels of the microbiome. The intricate mechanisms by which the microbiota influences immune responses to HIV are still poorly under… Show more
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