From Collagen Mimetics to Collagen Hybridization and Back
Pahweenvaj Ratnatilaka Na Bhuket,
Yang Li,
S. Michael Yu
Abstract:Conspectus
Facilitated by the unique triple-helical protein
structure, fibrous
collagens, the principal proteins in animals, demonstrate a dual function
of serving as building blocks for tissue scaffolds and as a bioactive
material capable of swift renewal in response to environmental changes.
While studies of triple-helical collagen mimetic peptides (CMPs) have
been instrumental in understanding the molecular forces responsible
for the folding and assembly of triple helices, as well as identifying
bioactive r… Show more
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