2008
DOI: 10.1007/s11249-008-9306-5
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Friction Coefficient Measurement of Hydrogel Materials on Living Epithelial Cells

Abstract: Soft biomaterials are often used in applications that involve contact and relative motion against biological tissues, as well as complicated and variable environments. The friction coefficient of these contacts involving living human cells is of key importance in the analysis and success of these devices. This work measures the contacting friction coefficient between soft hydrogel biomaterial surfaces against live human corneal epithelial cells using a custom micro-tribometer. The friction coefficients were of… Show more

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Cited by 60 publications
(42 citation statements)
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“…No further analysis of elastic contact in the absence of adhesion for the Winkler foundation will be explicitly developed in this article as it has been done before by others [11,28,29]. This derivation is based on a conservation of energy, and it is therefore necessary to find an expression for the strain energy stored in the compressive region of contact, U 0 .…”
Section: Modeling Of Contact With Adhesion In the Compressive Contactmentioning
confidence: 99%
“…No further analysis of elastic contact in the absence of adhesion for the Winkler foundation will be explicitly developed in this article as it has been done before by others [11,28,29]. This derivation is based on a conservation of energy, and it is therefore necessary to find an expression for the strain energy stored in the compressive region of contact, U 0 .…”
Section: Modeling Of Contact With Adhesion In the Compressive Contactmentioning
confidence: 99%
“…However, issues concerning end-of-day comfort still exist [2]. Discomfort caused by contact lenses has been related to several factors such as dryness, protein adsorption, physiological factors and friction occurring during the blinking process, especially between the anterior side of the lens and the inner eyelid [3][4][5][6][7][8]. Clinical tests have been performed to understand and improve comfort, and have centered on the trial of different lens materials and ophthalmic solutions [9][10][11][12][13].…”
Section: Introductionmentioning
confidence: 99%
“…Hydrogel Friction -Hydrogels are readily observed to be very slippery and have been shown to have very low friction coefficient with glass or plastic substrates [22,23,24]. We mesure the friction coefficient of a hydrogel-hydrogel (HH) contact by stacking two dyed polyacrylamide hydrogel cubes (Educational Innovations) on top of each other in a demineralized water bath.…”
Section: Using Hydrogel Spheresmentioning
confidence: 99%