Fri0529 is Cotrimoxazole Prophylaxis Against Pneumocistis Jirovencii Pneumonia Recommended in Patients With Systemic Autoimmune Diseases Requiring Immunosuppressive Therapies? A Systematic Literature Review.
Abstract:Background:The incidence of Pneumocistis jirovencii pneumonia (PCP) has increased substantially during the past years in patients with systemic autoimmune diseases (SAD). Mortality associated to PCP was reported to be up to 20 to 58%, particularly in those receiving immunosuppressive therapy, such as tumoral necrosis antagonist factors or glucocorticoid therapy. Though, there is clear evidence of the effectiveness of Cotrimoxazole against PCP, the risk of adverse effects is important, increasing morbidity and … Show more
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