Frey Procedure in Patients with Chronic Pancreatitis: Short and Long-term Outcome from a Prospective Study

Abstract

The Frey procedure is an appropriate, safe and effective technique for management of patients with chronic pancreatitis in the absence of neoplasia, based on long-term follow-up.

Frey procedure combined with biliary diversion in chronic pancreatitis

“…The mean rate of severe morbidity (20%) was acceptable and mortality was nil. Those rates are in line with the previously published prospective series [11][12][13] . Therefore, this series confirms that PD is not necessary even when CBD obstruction is associated with a pancreatic head mass.…”

Frey procedure for chronic pancreatitis in children: A single center experience

“…CP in children is often unresponsive to medical therapy and may result in addiction to pain medication, dietary restrictions, and absences from school, and significant impairment of quality of life [1,2]. Steatorrhea and diabetes mellitus develop in the long term [3]. Thirty to fifty percent of patients require surgery during their lifetime.…”

“…But in the past two decades, procedures like Beger and Frey procedures are most commonly performed operations for CP. Although, the results of Frey procedure are well characterized in adults [1,3]; there is limited data in children and adolescents. To the best of our knowledge, only one small case series [2] has been published in the English literature till date.…”

“…To the best of our knowledge, only one small case series [2] has been published in the English literature till date. Given its safety and efficacy in adults [3], the Frey procedure has become our preference for the surgical management of chronic pancreatitis in children.The goal of this study is to report our experience with the Frey procedure for the management of CP in children.…”

“…In our cases the mean duration between the onset of disease and the surgery was 4.4 years and median follow-up was 29 months only. Regarding pancreatic endocrine function, previous reports[3,8] showed that 10-20% of patients had new-onset diabetes mellitus after the Frey procedure. These are all adult series.…”