Frequency, types and severity of medication use-related problems among medical outpatients in Nigeria

Yusuff, Kazeem B.; Tayo, Fola

doi:10.1007/s11096-011-9508-z

Cited by 21 publications

(18 citation statements)

References 16 publications

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“…While this statistic is relatively new, we chose to report it because we felt it more accurately reflected the true agreement in our study, as many of the answers to bleeding symptoms on the Condensed MCMDM‐1VWD did not have equal distributions. Other researchers have addressed the same issue and support the use of Gwet's AC1 as a measure of inter‐rater reliability .…”

Section: Discussionmentioning

confidence: 99%

The accuracy of a patient or parent‐administered bleeding assessment tool administered in a paediatric haematology clinic

et al. 2014

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Classifying and describing bleeding symptoms is essential in the diagnosis and management of patients with mild bleeding disorders (MBDs). There has been increased interest in the use of bleeding assessment tools (BATs) to more objectively quantify the presence and severity of bleeding symptoms. To date, the administration of BATs has been performed almost exclusively by clinicians; the accuracy of a parent-proxy BAT has not been studied. Our objective was to determine the accuracy of a parent-administered BAT by measuring the level of agreement between parent and clinician responses to the Condensed MCMDM-1VWD Bleeding Questionnaire. Our cross-sectional study included children 0-21 years presenting to a haematology clinic for initial evaluation of a suspected MBD or follow-up evaluation of a previously diagnosed MBD. The parent/caregiver completed a modified version of the BAT; the clinician separately completed the BAT through interview. The mean parent-report bleeding score (BS) was 6.09 (range: -2 to 25); the mean clinician report BS was 4.54 (range: -1 to 17). The mean percentage of agreement across all bleeding symptoms was 78% (mean κ = 0.40; Gwet's AC1 = 0.74). Eighty percent of the population had an abnormal BS (defined as ≥2) when rated by parents and 76% had an abnormal score when rated by clinicians (86% agreement, κ = 0.59, Gwet's AC1 = 0.79). While parents tended to over-report bleeding as compared to clinicians, overall, BSs were similar between groups. These results lend support for further study of a modified proxy-report BAT as a clinical and research tool.

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Section: Discussionmentioning

confidence: 99%

The accuracy of a patient or parent‐administered bleeding assessment tool administered in a paediatric haematology clinic

et al. 2014

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“…Most recently published articles that have assessed inter-rater reliability have used Cohen’s Kappa exclusively [19-26], and a recent review of the current methods used for inter-rater reliability does not even mention AC1 [27]. During our research of PubMed (up to February 2013), we found only 2 published articles that mention using Gwet’s AC1 method as part of a study [28,29]. …”

Section: Discussionmentioning

confidence: 99%

A comparison of Cohen’s Kappa and Gwet’s AC1 when calculating inter-rater reliability coefficients: a study conducted with personality disorder samples

Wongpakaran

Wedding

et al. 2013

BMC Med Res Methodol

684

476

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“…found that ‘wrong drug’, ‘need for additional drug’ and ‘taking too little of the drug’ were the most frequent TRPs. A study conducted in Nigeria identified ‘nonadherence’ and ‘adverse drug reactions’ as the main TRPs …”

Section: Discussionmentioning

confidence: 99%

Revealing treatment-related problems for outpatients with alarming health status in the United Arab Emirates

Basheti

Abu‐Gharbieh

2017

J Pharm Health Serv Res

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Objectives To explore types and frequencies of treatment‐related problems (TRPs) amongst outpatients with chronic diseases recruited through community pharmacies and clinics in the UAE via conducting the medication management review (MMR) service. Methods This observational study was conducted over three months in 2013 in the UAE. Ethical approval was obtained, and patients were recruited randomly by two pharmacists from different outpatient settings. Patient interview was conducted at the community pharmacy or clinic to collect demographic data, followed by a visit to the patient's home to collect the medical data. TRPs for each patient were identified by the clinical pharmacist. Key findings A total of 125 patients (mean age: 52.40 ± 12.60) completed the study. More than half of the patients (57%) were classified overweight (BMI > 24.90 kg/m2), and many (22%) were smokers. Mean number of medical conditions was 2.77 ± 1.44; mean number of medications taken was 3.12 ± 1.29. Most prevalent diseases included diabetes mellitus (24%), hypertension (21%), coronary artery disease (11%) and asthma (9%). Mean number of identified TRPs was 1.76 ± 1.44 per patient. The most common TRP categories were inappropriate adherence (68.5%), inappropriate dosage regimen (35.4%), untreated conditions (29.2%) and ineffective/incomplete drug therapy (26.2%). Conclusions Prevalence of TRPs among outpatients living in the UAE is a concern that needs addressing. None adherence is a major TRP amongst patients with chronic conditions. The MMR service delivered by pharmacists is needed to identify, prevent and resolve outpatients’ TRPs.

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Frequency, types and severity of medication use-related problems among medical outpatients in Nigeria

Abstract: Potentially harmful medication use-related problems are frequently encountered among medical outpatients in Nigeria. The institutionalization of medication use review and the devolution of this task to pharmacists may prove beneficial in optimizing outcomes of medication use in Nigeria.

Cited by 21 publications

References 16 publications

The accuracy of a patient or parent‐administered bleeding assessment tool administered in a paediatric haematology clinic

The accuracy of a patient or parent‐administered bleeding assessment tool administered in a paediatric haematology clinic

A comparison of Cohen’s Kappa and Gwet’s AC1 when calculating inter-rater reliability coefficients: a study conducted with personality disorder samples

Revealing treatment-related problems for outpatients with alarming health status in the United Arab Emirates

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