Frequency-specific altered global signal topography in drug-naïve first-episode patients with adolescent-onset schizophrenia

Wang, Xiao; Liao, Wei; Han, Shaoqiang; Li, Jiao; Wang, Yifeng; Zhang, Yan; Zhao, Jingping; Chen, Huafu

doi:10.1007/s11682-020-00381-9

Cited by 10 publications

(7 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results obtained from the GSCORR matrix indicated higher values primarily in the posterior sensory cortices, which encompassed regions in the occipital, parietal, and temporal lobes, while the lowest values were observed in the association cortex (e.g., regions in the frontal and temporal lobes belonging to the frontoparietal network and default mode network) and subcortical regions (Figure 1a ). These findings were consistent with previous studies (Wang, Liao, et al, 2020 ; Yang et al, 2017 ; Zhang et al, 2020 ). The coherence curve showed a bi‐peak distribution, which aligned with previous coherence studies (Drew et al, 2008 ; Li et al, 2015 ; Wang et al, 2016 ; Wang, Zou, et al, 2020 ).…”

Section: Resultssupporting

confidence: 94%

“…Protocol 3 (strict control for physiological factors, Figure 3) Protocol 4 (no control for physiological factors, Figure 3) frontal and temporal lobes belonging to the frontoparietal network and default mode network) and subcortical regions (Figure 1a). These findings were consistent with previous studies (Wang, Liao, et al, 2020;Yang et al, 2017;Zhang et al, 2020). The coherence curve showed a bi-peak distribution, which aligned with previous coherence studies (Drew et al, 2008;Li et al, 2015;Wang et al, 2016;Wang, Zou, et al, 2020).…”

Section: Spatiotemporal Dedifferentiation Of Gs Topographysupporting

confidence: 93%

“…In the short time scale, frequency‐specific FC has been widely identified to be a core neurophysiological mechanism of brain function (Adaikkan et al, 2019 ; Buzsáki, 2006 ; Fiebelkorn & Kastner, 2019 ; Han et al, 2017 ; Perrault et al, 2019 ; Wang et al, 2016 ; Watrous et al, 2013 ). For example, frequency‐specific alteration of the GS topography has been observed in patients with schizophrenia (Wang, Liao, et al, 2020 ). On the other hand, the human lifespan, as the largest time scale of dynamic brain development, dominates and changes the functional organization of the whole brain (Cao et al, 2014 ; Vij et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan

Ao,

Yang,

Drewes

et al. 2023

Human Brain Mapping

Self Cite

View full text Add to dashboard Cite

Age‐related variations in many regions and/or networks of the human brain have been uncovered using resting‐state functional magnetic resonance imaging. However, these findings did not account for the dynamical effect the brain's global activity (global signal [GS]) causes on local characteristics, which is measured by GS topography. To address this gap, we tested GS topography including its correlation with age using a large‐scale cross‐sectional adult lifespan dataset (n = 492). Both GS topography and its variation with age showed frequency‐specific patterns, reflecting the spatiotemporal characteristics of the dynamic change of GS topography with age. A general trend toward dedifferentiation of GS topography with age was observed in both spatial (i.e., less differences of GS between different regions) and temporal (i.e., less differences of GS between different frequencies) dimensions. Further, methodological control analyses suggested that although most age‐related dedifferentiation effects remained across different preprocessing strategies, some were triggered by neuro‐vascular coupling and physiological noises. Together, these results provide the first evidence for age‐related effects on global brain activity and its topographic‐dynamic representation in terms of spatiotemporal dedifferentiation.

show abstract

Section: Resultssupporting

confidence: 94%

Section: Spatiotemporal Dedifferentiation Of Gs Topographysupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan

Ao,

Yang,

Drewes

et al. 2023

Human Brain Mapping

Self Cite

View full text Add to dashboard Cite

show abstract

“…Stasa D. et al reported that temporal lobe was activated obviously during infusion of fluid in the bladder 47 . Lingna Zhao et al also found that the functional connectivity between the temporal gyrus and the insula was enhanced when the bladder was full 48 . Detrusor overactivity was a feature of NE children 49 .…”

Section: Discussionmentioning

confidence: 95%

Frequency-specific alterations of the resting-state BOLD signals in nocturnal enuresis: an fMRI Study

Zheng

Sun

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Resting state functional magnetic resonance imaging studies of nocturnal enuresis have focused primarily on regional metrics in the blood oxygen level dependent (BOLD) signal ranging from 0.01 to 0.08 Hz. However, it remains unclear how local metrics show in sub-frequency band. 129 children with nocturnal enuresis (NE) and 37 healthy controls were included in this study. The patients were diagnosed by the pediatricians in Shanghai Children’s Medical Center affiliated to Shanghai Jiao Tong University School of Medicine, according to the criteria from International Children's Continence Society (ICCS). Questionnaires were used to evaluate the symptoms of enuresis and completed by the participants. In this study, fALFF, ReHo and PerAF were calculated within five different frequency bands: typical band (0.01–0.08 Hz), slow-5 (0.01–0.027 Hz), slow-4 (0.027–0.073 Hz), slow-3 (0.073–0.198 Hz), and slow-2 (0.198–0.25 Hz). In the typical band, ReHo increased in the left insula and the right thalamus, while fALFF decreased in the right insula in children with NE. Besides, PerAF was increased in the right middle temporal gyrus in these children. The results regarding ReHo, fALFF and PerAF in the typical band was similar to those in slow-5 band, respectively. A correlation was found between the PerAF value of the right middle temporal gyrus and scores of the urinary intention-related wakefulness. Results in other bands were either negative or in white matter. NE children might have abnormal intrinsic neural oscillations mainly on slow-5 bands.

show abstract

“…Moreover, GST can be modulated by individual factors, like conscious state and attention-demanding tasks (Ao et al, 2021 ). In addition, abnormal GST has been detected in patients with bipolar disorder, schizophrenia, epilepsy, and major depressive disorder (Li et al, 2019 , 2021 ; Wang et al, 2021 ). Together, these findings suggest a mechanistic insight into how GST and local neural activity coordinate to organize layers of information in the brain.…”

Section: Introductionmentioning

confidence: 99%

Altered Global Signal Topography in Alcohol Use Disorders

Duan

Jing

et al. 2022

Front. Aging Neurosci.

View full text Add to dashboard Cite

The most common symptom of patients with alcohol use disorders (AUD) is cognitive impairment that negatively affects abstinence. Presently, there is a lack of indicators for early diagnosis of alcohol-related cognitive impairment (ARCI). We aimed to assess the cognitive deficits in AUD patients with the help of a specific imaging marker for ARCI. Data-driven dynamic and static global signal topography (GST) methods were applied to explore the cross-talks between local and global neuronal activities in the AUD brain. Twenty-six ARCI, 54 AUD without cognitive impairment (AUD-NCI), and gender/age-matched 40 healthy control (HC) subjects were recruited for this study. We found that there was no significant difference with respect to voxel-based morphometry (VBM) and static GST between AUD-NCI and ARCI groups. And in dynamic GST measurements, the AUD-NCI patients had the highest coefficient of variation (CV) at the right insula, followed by ARCI and the HC subjects. In precuneus, the order was reversed. There was no significant correlation between the dynamic GST and behavioral scores or alcohol consumption. These results suggested that dynamic GST might have potential implications in understanding AUD pathogenesis and disease management.

show abstract

Frequency-specific altered global signal topography in drug-naïve first-episode patients with adolescent-onset schizophrenia

Cited by 10 publications

References 68 publications

Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan

Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan

Frequency-specific alterations of the resting-state BOLD signals in nocturnal enuresis: an fMRI Study

Altered Global Signal Topography in Alcohol Use Disorders

Contact Info

Product

Resources

About