Frequency of specific anti-Toxoplasma gondii IgM, IgA and IgE in Colombian patients with acute and chronic ocular toxoplasmosis

Abstract

We studied the frequency of specific anti-Toxoplasma IgM, IgA

A Multihousehold Study Reveals a Positive Correlation between Age, Severity of Ocular Toxoplasmosis, and Levels of Glycoinositolphospholipid‐Specific Immunoglobulin A

“…This prevalence is similar to that noted in other studies performed in South America (e.g., in Brazil and Colombia) [25][26][27][28][29][30]. The prevalence of 47% (95% CI, 31%-61%) that was noted for children !10 years of age is considered to be high, compared with that observed in studies performed in Europe and North America [2,31]; however, it is similar to that noted in studies in Africa [32] and Asia [33].…”

A Multihousehold Study Reveals a Positive Correlation between Age, Severity of Ocular Toxoplasmosis, and Levels of Glycoinositolphospholipid‐Specific Immunoglobulin A

“…This prevalence is similar to that noted in other studies performed in South America (e.g., in Brazil and Colombia) [25][26][27][28][29][30]. The prevalence of 47% (95% CI, 31%-61%) that was noted for children !10 years of age is considered to be high, compared with that observed in studies performed in Europe and North America [2,31]; however, it is similar to that noted in studies in Africa [32] and Asia [33].…”

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”

Toxoplasma gondii Elongation Factor 1-Alpha (TgEF-1α) Is a Novel Vaccine Candidate Antigen against Toxoplasmosis

“…In our study, high titers of IgA were detected in the sera of rTgEF-1α immunized group, indicating that rTgEF-1α has successfully induced the release of this antibody as part of the response generated after immunization. Immunoglobulins IgM and IgE aslo were reported to participate in the immunological responses against T. gondii infection ( Gomez-Marin et al, 2000 ; Lynch et al, 2011 ; Vouldoukis et al, 2011 ; Amin et al, 2012 ). However, our data revealed no significant changes of these two immunoglobulin after vaccination with rTgEF-1α.…”

A Multihousehold Study Reveals a Positive Correlation between Age, Severity of Ocular Toxoplasmosis, and Levels of Glycoinositolphospholipid‐Specific Immunoglobulin A

“…This prevalence is similar to that noted in other studies performed in South America (e.g., in Brazil and Colombia) [25][26][27][28][29][30]. The prevalence of 47% (95% CI, 31%-61%) that was noted for children !10 years of age is considered to be high, compared with that observed in studies performed in Europe and North America [2,31]; however, it is similar to that noted in studies in Africa [32] and Asia [33].…”

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”

Toxoplasma gondii Elongation Factor 1-Alpha (TgEF-1α) Is a Novel Vaccine Candidate Antigen against Toxoplasmosis

“…In our study, high titers of IgA were detected in the sera of rTgEF-1α immunized group, indicating that rTgEF-1α has successfully induced the release of this antibody as part of the response generated after immunization. Immunoglobulins IgM and IgE aslo were reported to participate in the immunological responses against T. gondii infection ( Gomez-Marin et al, 2000 ; Lynch et al, 2011 ; Vouldoukis et al, 2011 ; Amin et al, 2012 ). However, our data revealed no significant changes of these two immunoglobulin after vaccination with rTgEF-1α.…”

A Multihousehold Study Reveals a Positive Correlation between Age, Severity of Ocular Toxoplasmosis, and Levels of Glycoinositolphospholipid‐Specific Immunoglobulin A

“…This prevalence is similar to that noted in other studies performed in South America (e.g., in Brazil and Colombia) [25][26][27][28][29][30]. The prevalence of 47% (95% CI, 31%-61%) that was noted for children !10 years of age is considered to be high, compared with that observed in studies performed in Europe and North America [2,31]; however, it is similar to that noted in studies in Africa [32] and Asia [33].…”

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”

Toxoplasma gondii Elongation Factor 1-Alpha (TgEF-1α) Is a Novel Vaccine Candidate Antigen against Toxoplasmosis

“…In our study, high titers of IgA were detected in the sera of rTgEF-1α immunized group, indicating that rTgEF-1α has successfully induced the release of this antibody as part of the response generated after immunization. Immunoglobulins IgM and IgE aslo were reported to participate in the immunological responses against T. gondii infection ( Gomez-Marin et al, 2000 ; Lynch et al, 2011 ; Vouldoukis et al, 2011 ; Amin et al, 2012 ). However, our data revealed no significant changes of these two immunoglobulin after vaccination with rTgEF-1α.…”