Frequency of Primary Nonadherence to Acne Treatment

Anderson, Kristen; Dothard, Emily H.; Huang, Karen; Feldman, Steven R.

doi:10.1001/jamadermatol.2014.5254

Cited by 55 publications

(53 citation statements)

References 22 publications

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“…Similar to Anderson et al, 15 we found a decrease in primary nonadherence to dermatologic medication with use of e-prescriptions. We also found that, during the first 4 days from the index visit, patients with paper prescriptions had a higher rate of full adherence.…”

Section: Discussionsupporting

confidence: 90%

“…In dermatology, only a few, mostly small studies have specifically investigated primary nonadherence. [15][16][17] In this study, we measure primary nonadherence to dermatologic medications by examining prescription data from a large, urban county hospital system with an enclosed prescription environment. Patient and prescription characteristics were evaluated to assess factors associated with primary nonadherence.…”

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confidence: 99%

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Association Between Method of Prescribing and Primary Nonadherence to Dermatologic Medication in an Urban Hospital Population

2017

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IMPORTANCE Prescription underuse is associated with poorer clinical outcomes. A significant proportion of underuse is owing to primary nonadherence, defined as the rate at which patients fail to fill and pick up new prescriptions. Although electronic prescribing increases coordination of care and decreases errors, its effect on primary nonadherence is less certain.OBJECTIVES To analyze factors associated with primary nonadherence to dermatologic medications and study whether electronic prescribing affects rates of primary nonadherence. DESIGN, SETTING, AND PARTICIPANTSA retrospective review of medical records was conducted from January 1, 2011, to December 31, 2013, among a cohort of new patients prescribed dermatologic medications at a single, urban, safety-net hospital outpatient dermatology clinic. MAIN OUTCOMES AND MEASURESThe primary outcome was the overall rate of primary nonadherence, defined as filling and picking up all prescribed medications within a 1-year period, and the difference in primary nonadherence between patients who received electronic prescriptions and those who received paper prescriptions. Secondary outcomes included the association of primary nonadherence with sex, age, relationship status, primary language, race/ethnicity, and number of prescriptions.RESULTS A total of 4318 prescriptions were written for 2496 patients (mean [SD] age, 47.7 [13.2] years; 849 men and 1647 women). The overall rate of primary nonadherence was 31.6% (n = 788). Based on multivariable analysis, the risk of primary nonadherence was 16 percentage points lower among patients given an electronic prescription (15.2%) than patients given a paper prescription (31.5%). Primary nonadherence decreased with age (<30 y, 38.9%; 30-49 y, 35.3%; and 50-69 y, 26.3%), and then increased in elderly patients 70 years and older (31.9%). Of patients who were given 1, 2, 3, 4, or 5 prescriptions, rates of primary nonadherence were 33.1%, 28.8%, 26.4%, 39.8%, and 38.1%, respectively. Primary nonadherence decreased with age but then increased in elderly patients. Patients identifying English as their primary language had the highest rate of primary nonadherence (33.9%) compared with Spanish (29%) or other speakers (20.4%).CONCLUSIONS AND RELEVANCE Compared with paper prescriptions, electronic prescriptions were associated with less primary nonadherence. Number of prescriptions, language, race/ethnicity, and age were associated with increased rates of primary nonadherence. Efforts must be made to understand why primary nonadherence occurs, identify patients prone to primary nonadherence, and simplify medication regimens to maximize adherence and quality of care.

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Section: Discussionsupporting

confidence: 90%

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confidence: 99%

Association Between Method of Prescribing and Primary Nonadherence to Dermatologic Medication in an Urban Hospital Population

2017

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“…However, topical retinoids require repeated applications (once or twice daily for at least 3 months) and are burdened by several side‐effects, such as redness, sensitivity and dry skin. Those side‐effects together with the prolonged duration of therapy are responsible for the reduced compliance towards this kind of treatment …”

Section: Resultsmentioning

confidence: 99%

“…Those side-effects together with the prolonged duration of therapy are responsible for the reduced compliance towards this kind of treatment. 32 The largest study available regarding treatment options for FRD describes the efficacy of superpulsed carbon dioxide laser treatment in a cohort of 50 patients affected by FRD. 33 Laser vaporization of the epidermis was followed by extraction of Table 3 Local complication rate (expressed as percentage), with 95% CI, in the individual studies included in the meta-analysis.…”

Section: Treatmentmentioning

confidence: 99%

Favre–Racouchot disease: systematic review and possible therapeutic strategies

Paganelli

Mandel

Kaleci

et al. 2018

Acad Dermatol Venereol

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Favre-Racouchot disease (FRD) is a relatively common dermatosis induced by chronic sun exposure. FRD is clinically and histologically characterized by the presence of both comedones and cysts in the context of an elastotic degeneration of the dermis. Those lesions are mainly located in the face, especially in the malar and periorbital areas. Smoking and radiotherapy seem to play a role in the pathogenesis together with UV exposure. The disease affects predominantly the aged population and seems to be a problem of mainly aesthetic concern. No official guidelines are available for the treatment of FRD; most common therapeutic strategies are represented by topical retinoids and laser treatments. The goal of our review was to identify the principal clinical and epidemiological characteristics of FRD and to analyse all the therapeutic strategies available. We also focused our attention on the follow-up of this particular dermatosis. Our aim was therefore to suggest alternative possible strategies for both the treatment and the follow-up of these patients. Our data support the efficacy of carbon dioxide laser and topical retinoids in the setting of FRD, but we also suggest considering alternative treatments, such as plasma exeresis. We also recommend planning both a short-term and a long-term follow-up visit, as the majority of relapses is observed after 10-12 months.

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“…Studies have shown that prescription of a single product might improve compliance with acne treatment. [1520]…”

Section: Discussionmentioning

confidence: 99%

Over-the-counter and prescription medications for acne: A cross-sectional survey in a sample of university students in Saudi Arabia

Alshehri

Almutairi

Alomran

et al. 2017

Indian Dermatol Online J

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Introduction and Background:Acne is a very common dermatological condition found among the adolescent population in Saudi Arabia. Many patients with acne try various forms of self-medication, over the counter medicines (OTC), and prescription medicines for the same.Materials and Methods:This was a cross-sectional study among university students in the Kingdom of Saudi Arabia (KSA). A validated questionnaire was distributed to a convenience sample of university students to evaluate their knowledge and attitudes towards OTC (mainly) as well as prescription medicine for acne. Chi-square and multiple logistic regression tests were used for comparisons between groups.Results:Four hundred and twenty valid, completed questionnaires were obtained. A total of 220 (52.4%) used some type of OTC medications at least once, where as 108 (25.7%) used prescription medicines and 92 (21.9%) used both. The most common OTC medications used were cleansers by 250 participants (41.9%). Among prescription medicines, the most common were topical and oral antibiotics (11.4%). Bivariate and multivariate analysis showed that females are statistically more likely to use OTC medicines compared to males (Odds ratio: 1.7).Conclusion:The use of self-medications and OTC medications is common among university students in KSA. The most common OTC medicine used for acne was cleanser.

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Frequency of Primary Nonadherence to Acne Treatment

Abstract: Primary adherence to an acne treatment regimen is better when only 1 treatment is prescribed. Some patients may not complete acne treatment because 1 or more of their medications were never obtained.

Cited by 55 publications

References 22 publications

Association Between Method of Prescribing and Primary Nonadherence to Dermatologic Medication in an Urban Hospital Population

Association Between Method of Prescribing and Primary Nonadherence to Dermatologic Medication in an Urban Hospital Population

Favre–Racouchot disease: systematic review and possible therapeutic strategies

Over-the-counter and prescription medications for acne: A cross-sectional survey in a sample of university students in Saudi Arabia

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