Frequency of Peripartum Cardiomyopathy

Mielniczuk, Lisa; Williams, Kathryn; Davis, Darryl R.; Tang, Anthony; Lemery, Robert; Green, Martin S.; Gollob, Michael H.; Haddad, Haissam; Birnie, David H.

doi:10.1016/j.amjcard.2006.01.039

Cited by 243 publications

(220 citation statements)

References 21 publications

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“…HF presenting earlier than the last month of pregnancy may be part of the same spectrum of disease, despite not meeting traditional criteria, and these patients tend to have the same demographics, degree of cardiac dysfunction and prognosis (95). The incidence of PPCM varies widely geographically, ranging from an incidence of one per 2289 to one per 4000 live births in the United States (96,97), to an incidence of one per 300 live births in Haiti (96 (107,108) and oxidative stress linked to proteolysis' cleavage of prolactin into a potent cardiotoxic subfragment (109).…”

Section: Pregnancy and Chronic Cardiovascular Diseasementioning

confidence: 99%

The 2010 Canadian Cardiovascular Society guidelines for the diagnosis and management of heart failure update: Heart failure in ethnic minority populations, heart failure and pregnancy, disease management, and quality improvement/assurance programs

Howlett¹,

McKelvie²,

Costigan³

et al. 2010

Canadian Journal of Cardiology

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Section: Pregnancy and Chronic Cardiovascular Diseasementioning

confidence: 99%

The 2010 Canadian Cardiovascular Society guidelines for the diagnosis and management of heart failure update: Heart failure in ethnic minority populations, heart failure and pregnancy, disease management, and quality improvement/assurance programs

Howlett¹,

McKelvie²,

Costigan³

et al. 2010

Canadian Journal of Cardiology

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“…28 Peripartum cardiomyopathy (PPCM) is a rare but potentially lethal complication of pregnancy occurring in approximately 1:4000 live births in the United States. 29 PPCM is a form of dilated cardiomyopathy that is defined as deterioration in cardiac function presenting typically between the last month of pregnancy and up to 5 months postpartum with no other etiology evident. 30 Approximately 75% of cases are diagnosed within the first month postpartum and 45% present in the first week after birth.…”

Section: Pregnancy and Peripartum Cardiomyopathymentioning

confidence: 99%

Heart Failure in Women

Shin

Hamad

Murthy

et al. 2012

Clinical Cardiology

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Heart failure (HF) has steadily increased in prevalence and affects both males and females equally. Despite this, there has been a significant underrepresentation of women in large scale HF trials. This disparity has lead to a deficit in understanding important gender-based differences in pathophysiology, diagnosis and treatment strategies. We review these gaps and explore a biological basis for varying outcomes. Endogenous estrogen plays an important role in epidemiology and outcome. The administration of exogenous estrogen has had varied success in treatment and is outlined extensively below. Additionally, we highlight unique HF syndromes through pregnancy and important sex-specific issues concerning transplant and mechanical circulatory support. A central theme remains: there is a clear need for increased female recruitment in clinical trials, and more studies exploring the role of gender-based biology in HF treatment. IntroductionThe prevalence of heart failure (HF) has steadily increased and is now the leading cause of hospital admissions in the adult population in the United States. 1 Women constitute approximately one half of the patients hospitalized for HF, and deaths from HF contribute 35% of the total cardiovascular disease (CVD) mortality in women. 1 -3 Despite this, women have been historically under-represented in clinical HF trials. Although the population estimate of women among patients with HF in the Unites States is about 50%, only 17% to 23% of HF randomized controlled trials enrolled women. 4 This disparity has limited our understanding of gender-related differences in HF. The objective of this article is to review the relationships between sex and the epidemiology, etiology, clinical characteristics, therapeutic management, and outcomes in patients with HF.

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“…Etiyolojisi net olarak aydınlatılamamasına rağmen 30 yaş üzeri gebelik, multiparite, hipertansiyon ve eklampsi risk faktörleri arasındadır 3, [5][6][7][8] . PKM'nin klinik seyri tam düzelme ile kalp transplantasyonu ihtiyacı gerektiren son dönem kalp yetmezliği arasında geniş bir spektrumdadır 11 .…”

Section: Introductionunclassified

Birinci basamakta bir Peripartum Kardiyomiyopati vakası

Yakar¹,

Ertekin²,

Korkut³

2016

Aile Hekimliği Ve Palyatif Bakım

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ÖZETGiriş: Peripartum Kardiyomiyopati (PKM), gebeliğin son ayında ve doğumdan sonraki ilk 5 ay içerisinde, kalp genişlemesi ve kalp kasının zayıflaması sonucu ortaya çıkan konjestif kalp yetmezliği formudur. Otuz yaş ve üzeri gebelik, multiparite, kronik hipertansiyon ve eklampsi PKM gelişiminde önemli risk faktörleridir. Nefes darlığı, çarpıntı, halsizlik, alt extremitede ödem gibi hastalığın erken belirtileri, gebeliğin son dönemlerinde normal karşılaşılabilecek sorunlar olduğundan kalp yetmezliğinden ayırt edilemeyip erken tanı gözden kaçabilmektedir. PKM tanısı anamnez, fizik muayene ve ekokardiyografi ile konur. Vaka Sunumu: Otuzdört yaşındaki kadın hasta, bir aylık bebeğinin aşısını yaptırmak için aile hekimliği polikliniğimize müracaat etti. Hastanın nefes darlığı, çarpıntı ve öksürük şikayeti mevcuttu. Özgeçmişinden iki sağlıklı doğum yaptığı, soygeçmişinde ise annesinin Primer Hipertansiyon ve Tip 2 Diyabet hastası olduğu öğrenildi. Gebeliklerinde ve öncesinde herhangi bir hastalık veya ilaç kullanım öyküsü yoktu. Fizik muayenesinde kan basıncı 120/70mmHg, nabzı ritmik ve 122/dakika, kalp seslerinde üfürümü yok, her iki akciğer bazallerde ralleri mevcut, batın muayenesi doğal saptandı. Her iki alt ekstremitede ise gode bırakan ödemi mevcuttu. Anamnez derinleştirildiğinde çarpıntısının doğumdan iki hafta önce başladığı ve postpartum birinci haftada artış gösterdiği öğrenildi. Kalp yetmezliği ve pulmoner emboli ön tanıları düşünülerek kardiyoloji uzmanına sevk edilen hasta akut dekompanse kalp yetmezliği tanısıyla yoğun bakıma yatırılarak tedavi edildi. Sonuç: PKM gebelikte sık karşılaşılan çarpıntı ve nefes darlığı şikayetlerinin nonspesifik olması sebebiyle erken tanısı güç bir hastalıktır. Hastalığın 30 yaş üzeri annelerde daha sık ortaya çıkması ve günümüzde anne olma yaşının ileri yaşlara gelmesi sebebiyle birinci basamakta PKM'yle karşılaşma olasılığı artmaktadır. Aile hekimleri düşük prevalansta görülen bu hastalığın risk faktörlerini sorgulama, semptomlarını takip etme ve uzmanına danışma yöntemleriyle üstesinden gelebilir. Anahtar kelimeler: Aile hekimliği, gebelik, kardiyomiyopati, peripartum dönem, postpartum dönem ABSTRACT Introduction: Peripartum cardiomyopathy (PKM) is a form of congestive heart failure that results from an enlarging of the heart and a weakening of the heart muscle in the last month of pregnancy and in the first five months of the postnatal period. Major risk factors include pregnancy at >30 years of age, multiparity, chronic hypertension and eclampsia. Patients suffering from PKM generally present with symptoms akin to heart failure, and the condition can be considered normal during the late period of pregnancy. A diagnosis of PKM can be made from anamnesis, a physical examination and echocardiography. Case Presentation: A 34-year old female patient, visiting the family medicine polyclinic for vaccinations of her 1-month-old infant, was noted to be suffering from shortness of breath, palpitations and coughing. There was no medical history of any disease or medication before...

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Frequency of Peripartum Cardiomyopathy

Cited by 243 publications

References 21 publications

The 2010 Canadian Cardiovascular Society guidelines for the diagnosis and management of heart failure update: Heart failure in ethnic minority populations, heart failure and pregnancy, disease management, and quality improvement/assurance programs

The 2010 Canadian Cardiovascular Society guidelines for the diagnosis and management of heart failure update: Heart failure in ethnic minority populations, heart failure and pregnancy, disease management, and quality improvement/assurance programs

Heart Failure in Women

Birinci basamakta bir Peripartum Kardiyomiyopati vakası

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