Frequency of Occurrence of Cataract in Atopic Dermatitis

Cowan, Alfred; Klauder, Joseph V.

doi:10.1001/archopht.1950.00910010772015

Cited by 42 publications

(21 citation statements)

References 4 publications

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“…29 In another study, 25% of patients with atopic dermatitis had cataract, with PSC cataract being the most common type (50%) followed by anterior subcapsular cataract (25%) and total opacities (12.5%). 30,31 These authors also noted rapid progression of cataract during periods when the skin disease was active. 29,30 A breakdown of the blood-aqueous barrier and frequent eye rubbing may also be contributory factors.…”

Section: Discussionmentioning

confidence: 94%

“…30,31 These authors also noted rapid progression of cataract during periods when the skin disease was active. 29,30 A breakdown of the blood-aqueous barrier and frequent eye rubbing may also be contributory factors. 32,33 A literature review of population-based studies on risk factors for cataract has failed to reveal atopy as a risk factor for the development of cataract even in young and age-related cataract.…”

Section: Discussionmentioning

confidence: 94%

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A study to explore the risk factors for the early onset of cataract in India

Praveen

Shah

Vasavada

et al. 2009

Eye

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Purpose The aim of this study was to identify risk factors for the development of cataract in young patients. Settings The study was undertaken at Iladevi Cataract and IOL Research Centre, Ahmedabad, Gujarat, India. Methods In a clinic-based observational study, 340 consecutive patients in the age group of 30-45 years presenting with nuclear, cortical, posterior subcapsular (PSC), mixed, and posterior polar cataract were prospectively studied. A detailed history regarding sunlight exposure, atopy, diabetes, steroid intake, myopia, glaucoma, and uveitis was elicited. Results The mean age of the patients was 40.2±4.6 years; there were 202 men. The major risk factors were atopy (25.6%), idiopathic (19.1%), high myopia (12.4%), atopy with steroid intake (10.9%), steroid usage (7.4%), sunlight exposure (3.8%), and diabetes mellitus (3.2%). PSC was observed in 53.5% eyes. Multinomial logistic regression revealed that atopy (P ¼ 0.016), steroid usage (P ¼ 0.100), and diabetes mellitus (P ¼ 0.076) documented higher odds for PSC. High myopia (Po0.001) and sunlight exposure (P ¼ 0.003) documented higher odds for nuclear cataract.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 94%

A study to explore the risk factors for the early onset of cataract in India

Praveen

Shah

Vasavada

et al. 2009

Eye

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“…This finding supports the conclusion drawn by Brunsting et al [5] that atopic cataracts are bound up with the severer forms of atopic dermatitis. The great difference in the incidence of atop ic cataracts among various studies [2][3][4][5][6][7][8][9][10][11], therefore, may be partly due to the varying severity of dermatitis in the patients exam ined.…”

Section: Discussionmentioning

confidence: 99%

“…The ex amination was directed especially to the presence of cataracts. According to Cowen and Klauder [2], we re garded lenticular opacity in the anterior subcapsular zone or in the posterior subcapsular zone as atopic cataract.…”

Section: Methodsmentioning

confidence: 99%

“…Cataract is an important ocular compli cation in adolescent and young adult pa tients with atopic dermatitis [1,2], A review of the literature from various countries, however, revealed a great difference in the frequency of occurrence of cataracts in pa tients with this condition. The incidence of atopic cataracts has been reported to be 20% in Finland [3], 16% in England [4], 8-12% in the United States [2,5,6], 3% in Sweden [7], 2% in Czechoslovakia [8], 0.4% in Germany [9,10], and 0% in Denmark [11], It is not clear whether there are social factors or eth nic differences in the susceptibility to atopic cataracts.…”

Section: Introductionmentioning

confidence: 99%

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Atopic Cataracts in a Japanese Population

1985

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Atopic cataract was observed in 19 (12.4%) of 153 Japanese adolescent and young adult patients with atopic dermatitis. Of the 19 patients, 4 had gross cataract which produced impairment of vision, and 15 had incipient cataract which was not accompanied by visual impairment. Cataracts occurred most frequently in patients with severe atopic dermatitis. Cataract development had no relationship to the distribution of skin lesions, clinical course of dermatitis, personal history of respiratory atopy, serum IgE levels, or concomitant ichthyosis vulgaris.

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