Frequency of minimal hepatic encepalopathy inilleterate patients with compensated cirrhosis

Zuberi, Bader Faiyaz; Alvi, Haris; Zuberi, Faisal Faiyaz; Rasheed, Tazeen; Nawaz, Zunaira; Fatima-Tuz-Zohra,

doi:10.12669/pjms.323.9655

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…Chronic liver disease carries a huge burden at health care in Pakistan leading to many complications like ascites, encephalopathy, and varices. [14][15][16] Assessment of quality of life in these patients is of outmost importance. There are many modalities and different ways for treatment of physical ailments of a patient but that is not all needed for complete recovery of patient from any illness.…”

Section: Discussionmentioning

confidence: 99%

Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire

et al. 2022

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Objective: To present and validate psychometric properties of Urdu version CLDQ, yet another objective was to do exploratory factorial analysis (EFA) of CLDQ Urdu version. Methods: This Cross-sectional Analytical Study was conducted at Dr. Ruth K.M. Pfau Civil Hospital Karachi during the period Nov. 15, 2021 to Jan. 30, 2022. CLDQ Urdu questionnaire was self-administered by the patients. The questionnaire consisted of 29 items and responses were recorded on 7-point Likert type scale. Reliability testing was done by Cronbach’s α, test value of >0.7 is taken as reliable. Exploratory factor analysis (EFA) was conducted with principal component analysis with varimax rotation. Adequacies for conduction of EFA depended on Kaiser-Meyer-Olkin (KMO) value of ≥0.5 and Bartlett’s Test of Sphericity (BTS) of ≤0.05. Mean CLDQ Urdu scores were also compared with Child Class using ANOVA and post-hoc analysis was done. Results: A total of 320 patients were selected after informed consent. All conditions for adequate EFA were met (Cronbach’s α =.949; KMO = .846; BTS ≤.001). Mean CLDQ Urdu score was 156.74 in male and 133.27 in female (p<.001). Child Class-A had best quality of life with score of 186.63 ±6.91 and Child Class-C had the worst with scores of 109.78 ±21.33. EFA resulted in reduction of domains to 4 (Muscular Symptoms, Emotional Symptoms, Abdominal Symptoms & Somnolence) & reduced the number of items from 29 to 11. Conclusion: Urdu CLDQ version is validated in our settings. EFA resulted in reductions in number of domains and items. CLDQ Urdu showed that quality of life decreases significantly with Child Class. doi: https://doi.org/10.12669/pjms.39.1.6602 How to cite this: Hussain SM, Zuberi BF, Rasheed T, Ali FS, Majid E. Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire. Pak J Med Sci. 2023;39(1):---------. doi: https://doi.org/10.12669/pjms.39.1.6602 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire

et al. 2022

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“…This indicates that cholelithiasis is an acquired disease, developed by chronic environmental factors with significant aging effect. Additionally, the studies recommended that portal vein diameter of greater than 13 mm point out portal hypertension 32,33 . Greater frequency of cholelithiasis in cases with a portal vein diameter off higher than 13 mm was discovered in our study.…”

Section: Figure: 1 Frequency Of Gallstones In Patients With Chronic L...mentioning

confidence: 99%

Risk assessment of gallstone among indoor patients of chronic liver diseases secondary to Hepatitis C.

Sanaullah Kalwar,

Kailash Raj Makhejani,

Soomro

et al. 2019

j Muhammad Med Coll

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Introduction: Gallstones (GS) are widely reported as the major cause of mortality and morbidity globally.1 The frequency of GS in patients with chronic liver disease (CLD) is considerably higher than in the general population.1-7 Moreover, prevailing risk of gallstone is associated with disease frequency and severity in advance stages of CLD.1,3 The predictable local incidence of gallstones in CLD patients is approximately 24-31%.6-7 HCV is presumed to be the major cause of CLD in the local settings6-7. Despite high prevalence of GS and HCV CLD in our population, the occurrence of GS in HCV CLD cases has not been assessed so far. Objective: To assess gallstone disease in indoor patients of chronic liver diseases secondary to Hepatitis-C.Methodology: This cross-sectional study was carried out at Department of Gastroenterology, Liaquat National Hospital (LNH), Institute for postgraduate medical studies and health sciences, Karachi from January 2013 to July 2013. Totalof145 patients of chronic liver disease (CLD) secondary to Hepatitis C Virus (HCV) of either gender, regardless of duration of disease, having age more than 30 years were selected purposively. Structured questionnaire used for data collection. Ultrasonography was done to diagnose gallstones. The routine investigations such as platelet count, anti HCV antibodies, and prothrombin time (PT) were performed. SPSS version 20 was used to analyze data. Variables like gallstone was presented through percentages and frequencies, age as mean and SD. After stratification of age, gender and severity of liver disease, chi-square test was applied and p-value less than 0.05 was considered statistically significant.Results: The mean age of patients (n=145) was 54.8±9.4 years, whereas mean of males was 53.9±9.3 years and females were 56.2±9.5years. Among total cases86(59.3%) were males and59(40.7%) were females. The gallstones in male patients (n= 30, 58.8%) was higher than female patients (n=21, 41.2%). However, this difference with regards to gender, was not statistically significant (p-value=0.9). The Child-Pugh score with gallstones patients was (10.0±2.1) slightly higher than patients without gallstone (10.7±2.1). In patients with gallstone, Child’sPughclass-Cwasfoundin51(54.3%) patients, class-Bin37(39.4, %) and class-A in 6 (6.3%) patients. Conclusion: HCV infection is independent risk factor for gallstones in cirrhotic patients. Laparoscopic cholecystectomy in Child-Pugh A and B patients with symptomatic gallstone disease is a safe procedure. Keywords: Gallstones, HCVCLD, Child-Turcotte-Pugh, Cholecystectomy

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Frequency of minimal hepatic encepalopathy inilleterate patients with compensated cirrhosis

Cited by 2 publications

References 14 publications

Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire

Validation and exploratory factor analysis of Urdu Version of Chronic Liver Disease Questionnaire

Risk assessment of gallstone among indoor patients of chronic liver diseases secondary to Hepatitis C.

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