Frequency of Merozoite Surface Protein 2 (MSP2) Allelic Families and Sulphadoxine-Pyrimethamine (SP) Resistance Markers Among Pregnant Women in Delta State, Nigeria)

Achu, Chiamaka Evan; Nwaorgu, O. C.; Egbuche, Chukwudi Michael; Ezeagwuna, Dorothy Amuche; Ajibaye, Olusola; D, Aribodor

doi:10.11648/j.ajbio.20200801.12

AJBIO

2020

DOI: 10.11648/j.ajbio.20200801.12

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Frequency of Merozoite Surface Protein 2 (MSP2) Allelic Families and Sulphadoxine-Pyrimethamine (SP) Resistance Markers Among Pregnant Women in Delta State, Nigeria)

Chiamaka Evan Achu¹,

O. C. Nwaorgu²,

Chukwudi Michael Egbuche³

et al.

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Prompt and Accurate Diagnosis, A Veritable Tool in Malaria Elimination Efforts

Egbuche¹

2021

Current Topics and Emerging Issues in Malaria Elimination

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The concept of malaria elimination is to get rid of local transmission of malaria parasites in a defined geographical area. Among the measures required for malaria elimination is prompt and accurate diagnosis. Malaria diagnostic tools currently in use: clinical diagnosis, Malaria Rapid Diagnostic Tests (mRDT) and molecular diagnosis, have limitations. Clinical diagnosis can be used as first step in making prompt malaria diagnosis, but cannot confirm cases. Malaria RDTs satisfies the need for prompt diagnosis but has low accuracy in confirming cases. Accuracy of microscopy depends on making good blood films, and accurate film interpretation. Molecular diagnosis required for species-specific diagnosis of malaria parasites, and determination of genes that confers drug resistance to Plasmodium species is not available for routine use. As part of elimination efforts, there is development of mRDT kits that utilize urine or saliva instead of blood specimen, microscopy digital image recognition and different technologies for molecular diagnosis. So far, none of these diagnostic tools has satisfied the need for prompt and accurate diagnosis. It is therefore recommended that more than one diagnostic tool is needed for malaria elimination to be achieved in a given area. This will ensure early detection and treatment of cases, as well as prevent the re-establishment of transmission.

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Prompt and Accurate Diagnosis, A Veritable Tool in Malaria Elimination Efforts

Egbuche¹

2021

Current Topics and Emerging Issues in Malaria Elimination

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Frequency of Merozoite Surface Protein 2 (MSP2) Allelic Families and Sulphadoxine-Pyrimethamine (SP) Resistance Markers Among Pregnant Women in Delta State, Nigeria)

Cited by 1 publication

References 0 publications

Prompt and Accurate Diagnosis, A Veritable Tool in Malaria Elimination Efforts

Prompt and Accurate Diagnosis, A Veritable Tool in Malaria Elimination Efforts

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