Frequency of Malignancy in Solitary Thyroid Nodule in a Tertiary Level Hospital of Bangladesh

Abstract

Objectives: To determine the frequency of thyroid malignancy in clinically and sonographically solitary thyroid nodule in patients undergoing thyroidectomy in Comilla Medical College Hospital. Methods: A cross sectional study was carried out at the Department of Otolaryngology and Head Neck Surgery of Comilla Medical College Hospital during the period from January 2016 to January 2019. This study includes all patients admitted and undergoing surgery with solitary thyroid nodule. Results: Out of 188 patients 146 patients were female and 42 patients were male with female:male ratio of 3.4:1. Out of 188 patients 24 patients were found histologically thyroid malignancy. Among them 14 patients were male and 10 patients were female. Papillary carcinoma was found in all cases. Conclusions: Follicular carcinoma is rare in our country. Histopathological examiners may not efficiently be doing their job to differentiate carcinoma from adenoma.

Predictive Validity of High-Resolution Ultrasonography as Compared to FNAC in Diagnosing Malignancy among Solitary Thyroid Nodules

“…12 A cross sectional study done in Bangladesh gave results that among 188 study subjects 24 found with histologically thyroid malignancy. 13 A study which was performed on 141 patients with true solitary thyroid nodules undergoing bilateral total thyroidectomy reported irregular borders, microcalcification, increased vascularity, and detection of cervical lymphadenopathy were found to be correlated with malignancy in solitary nodules. 14 Present study gave us finding that 68% of population had benign lesions incidence with solitary thyroid nodule.One study showed that Solitary Nodule of Thyroid was more common in female participants with incidence of Malignancy of 8%.…”