Frequency of idiopathic aseptic necrosis in medically treated alcoholics

Orlić, Dubravko; Jovanović, Savo; Antičević, Darko; Zečević, Josip

doi:10.1007/bf00182650

Cited by 32 publications

(15 citation statements)

References 12 publications

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“…ON, especially of the femoral head, in association with chronic alcoholism is fairly common. The incidence rate among alcoholics may not be as high as expected with the incidence of 5.3% in medically treated alcoholics (28,29). Radiographic and pathologic characteristics of ON in patients with aplastic anemia are not unique, being evident in cases of bony necrosis due to other causes.…”

Section: Discussionmentioning

confidence: 88%

Osteonecrosis of the Hip in Patients with Aplastic Anemia

et al. 2002

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The incidence and clinical and magnetic resonance imaging features of osteonecrosis of the hip were evaluated in patients with aplastic anemia. Two hundred and forty-one patients with aplastic anemia were examined using MR imaging of bone marrow during the five years from 1994 to 1998. Osteonecrosis of the hip was observed on MR imaging in nineteen (15 males and 4 females, mean age 35 yr) of the 241 patients. It was present in both hips in 14 patients, and there were five cases with unilateral occurrence, with a total of 33 involved hips. All except for five hips with associated bone marrow edema revealed increased fatty marrow conversion in the proximal femoral metaphysis. In nine patients, osteonecrosis was detected without any pain. Five patients already had osteonecrosis before any medication was administered. Twelve patients received antilymphocyte globulin, and seven patients received a low dose of steroids before the MR diagnosis of osteonecrosis. Osteonecrosis of the hip frequently develops in patients with aplastic anemia (7.9%), associated with fatty marrow conversion of the proximal femoral metaphysis.

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Section: Discussionmentioning

confidence: 88%

Osteonecrosis of the Hip in Patients with Aplastic Anemia

et al. 2002

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“…The incidence of ON in persons who have had medical treatment for excessive consumption of alcohol was reported to be 5.3 % (62/1157) by Orlic et al [13]. They found that patients with alcohol-associated ON had femoral head involvement in 89.1 % and multiple foci in 6.1 %.…”

Section: Alcoholmentioning

confidence: 99%

Osteonecrosis of the femoral head: diagnosis and classification systems

Choi

Steinberg

Cheng

2015

Curr Rev Musculoskelet Med

100

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Osteonecrosis of femoral head is a rare but disabling condition that usually results in progressive femoral head collapse and secondary arthritis necessitating total hip arthroplasty if not treated appropriately in early stages. However, early diagnosis is challenging as the onset of disease is insidious and the symptoms and signs are usually minimal and nonspecific until it becomes advanced. Of several diagnostic modalities, magnetic resonance imaging (MRI) is considered the imaging method of choice with the highest sensitivity and specificity, while detection of potential risk factors is very important as well. Many investigators have developed several different classification systems; however, there still is controversy regarding the optimal classification system. Diagnostic methods and the evolution of different classification systems will be reviewed in this paper.

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“…Chronic alcohol intake is a common cause of ON; however, multifocal ON is relatively rare. In 1990, Orlić et al [8] reported an incidence of ON in 5.3% of alcoholics, with 6.1% of these being multifocal. In our case, the patient consumed up to 200 mL of alcohol per week.…”

Section: Discussionmentioning

confidence: 99%

Multifocal Osteonecrosis in a Patient with Gout: Case Report and Review of the Literature

Kang

Lee

2017

J Rheum Dis

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Osteonecrosis (ON) is a common comorbidity in gout; however, avascular ON of multiple sites is unusual. Multifocal ON is defined as osteonecrotic lesions affecting three or more separate anatomic sites. We report a case of a 31-year-old woman diagnosed with gout, who had multifocal ON. Initially, she was treated with benzbromarone, colchicine, and meloxicam. Two years later, she developed severe tophi and was diagnosed with chronic renal failure. Magnetic resonance imaging (MRI) of both legs revealed bilateral ON of the femoral head. She underwent bilateral hip replacement surgeries. After two years, she had pain and limited movements in the left shoulder, with tophi identified via dual-energy computed tomography. Despite management with non-steroidal anti-inflammatory drugs, colchicine, and prednisolone, she had persistent shoulder pain. MRI of the left shoulder revealed ON. She therefore underwent left shoulder replacement surgery. Following the case report, we review the literature on multifocal ON with gout. (J Rheum Dis 2017;24:246-250)

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Frequency of idiopathic aseptic necrosis in medically treated alcoholics

Cited by 32 publications

References 12 publications

Osteonecrosis of the Hip in Patients with Aplastic Anemia

Osteonecrosis of the Hip in Patients with Aplastic Anemia

Osteonecrosis of the femoral head: diagnosis and classification systems

Multifocal Osteonecrosis in a Patient with Gout: Case Report and Review of the Literature

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