Frequency of Helicobacter Pylori Infection and Giardiasis in Children of Different Age Groups With Abdominal Pain and Dyspeptic Syndrome According to the Fecal Immunochromatographic Method

Nemchenko, U. M.; Grigorova, E. V.; Иванова, Е. И.; Kungurtseva, E. A.; Tunik, T. V.; Савелькаева, М. В.; Петрова, И. В.; Rychkova, L. V.

doi:10.22625/2072-6732-2018-10-1-24-28

Cited by 2 publications

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“…Another study conducted in Yemen revealed that Giardia was detected only in 10% of children with abdominal complaints (recurrent and chronic abdominal pain, gastritis, dyspepsia, nausea, vomiting, chronic diarrhea) with prevalence among younger children (<5 years) [16]. In our study Giardia-positive children were older (10.6±3.4 years) which also concurred with another study [14]. Also according to Turkish data, 30.6% of children with recurrent abdominal pain were Giardia-positive [13].…”

Section: Serum Interleukin-4 (Il-4) Levels In the Gastroduodenal Disorders (Gdd) Group In Relation To Infections With Helminths Giardia Osupporting

confidence: 91%

“…According to our results, H. py- lori infection was confirmed in 33.3% of the GDD group while other researchers have estimated it is from 50% to 70% depending on the region studied [2,3,10,13]. However, some studies found the same rates of H. pylori infections in children with abdominal pain and dyspeptic syndrome [14,15], as in our study. These findings confirm that the frequency of H. pylori infection varies depending on the region.…”

Section: Discussionsupporting

confidence: 78%

“…These findings can be explained by the fact that both H. pylori and parasites share the same estimated risk factors (poor hygiene and sanitation, low socioeconomic conditions) [15]. Several studies have reported the relationship of co-infection between Giardia and H. pylori in symptomatic and asymptomatic patients, but the frequency of such co-infection was different [4,12,[14][15][16][17][18]. The study conducted in Turkey showed that the frequency of co-infection between H. pylori and Giardia in symptomatic children was 22.4% compared to 6.8% in the control group [13].…”

Section: Serum Interleukin-4 (Il-4) Levels In the Gastroduodenal Disorders (Gdd) Group In Relation To Infections With Helminths Giardia Omentioning

confidence: 99%

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Clinical and immunological peculiarities of parasitic infections in children with digestive system disorders in Western Ukraine

Hlushko¹,

Pavlyshyn²,

Kozak³

2021

Ukr.Biochem.J

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Diseases of the digestive system such as gastroduodenal disorders (GDD) and hepatobiliary diseases (HBD) are fairly common among children. At the same time, intestinal parasites are widespread gastrointestinal tract infectious agents. We examined 108 children with GDD (n = 54) and HBD (n = 54) (mean age 11.8 ± 4.3 years) who were treated in a children's hospital. The following were performed: blood test for specific Ig to Ascaris lumbricoides, Toxocara canis; feces analysis for helminth eggs, Giardia cysts; and pinworm test. The serum level of interleukin-4 (Il-4) was measured in 97 of 108 children. overall parasitic co-infections were found in 60.2% of children: giardiasis in 30.6%, toxocariasis in 17.6%, ascariasis seropositivity in 13.9% and enterobiasis in 8.3% of cases. Parasitic infections (PIs) occurred in 72.2% of the HBD group and in 48.2% of the GDD group (P = 0.01). Among the PIs only ascariasis was found more often in the HBD group (22.2%) compared with the GDD group (5.6%) (P = 0.01). The mean age of children who were positive for PI (PI+) was 9.9 ± 4.6 years; while in the PI negative (PI-) group the mean age was 12.8 ± 3.3 years (P < 0.001). In GDD the Il-4 level in PI+ group was 9.3 ± 0.9 pg/ml in the versus 6.9 ± 1.8 pg/ml in the PI-group (P = 0.02). Children with HBD and PI had higher .8 pg/ml) compared to those without PI (7.5 ± 2.4 pg/ml) (P = 0.03). The differing impact on the course and immune response in children depending on co-infection with PIs indicates the need for additional testing for these infections. K e y w o r d s: children, parasitic infections, digestive diseases, interleukin-4.

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Section: Serum Interleukin-4 (Il-4) Levels In the Gastroduodenal Disorders (Gdd) Group In Relation To Infections With Helminths Giardia Osupporting

confidence: 91%

Section: Discussionsupporting

confidence: 78%

Section: Serum Interleukin-4 (Il-4) Levels In the Gastroduodenal Disorders (Gdd) Group In Relation To Infections With Helminths Giardia Omentioning

confidence: 99%

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Clinical and immunological peculiarities of parasitic infections in children with digestive system disorders in Western Ukraine

Hlushko¹,

Pavlyshyn²,

Kozak³

2021

Ukr.Biochem.J

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“…The prevalence of H. pylori infection among teenagers of 14-16 years old was 33.3%. The literature data about contagion of teenagers in other regions vary from 33-45 to 94.0% [5,8,9]. Thus, the rate of infection with H. pylori increases with the age of the population, however, this requires active prophylactic measures among children also, beginning from preschool and school age.…”

Section: Methodsmentioning

confidence: 99%

Prevalence rate of Helicobacter pylori infection among population of Ryazan region

Жесткова

Васильевна²,

Butov

et al. 2019

I.P. Pavlov Russian Medical Biological Herald

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Aim. Determination of the prevalence of Helicobacter pylori (H. pylori) infection among the population of the Ryazan region. Materials and Methods. 833 individuals (809 adults and 24 children) were examined for presence of IgG class antibodies using the enzyme immunoassay (2017-2018). The criteria for inclusion into the study were: a desire of a patient to undergo examination for the presence of antibodies to H. pylori in blood. Criteria for exclusion: past treatment for helicobacteriosis. The presence of helicobacteriosis was determined by enzyme immunoassay for quantitative detection of IgG class antibodies (anti-H. pylori IgG) using BCM Diagnostics Helicobacter pylori IgG (USA) test system and for qualitative determination of IgG antibodies to H. pylori in blood serum on IMMULITE 2000 (Germany; test IMMULITE 2000 H. pylori IgG). Sensitivity of the used test systems was 95.0%, specificity 98.0%. Results. High contamination of adult residents of Ryazan with H. pylori 65.6% was found (70.6% of males, 64.4% of females). Prevalence of H. pylori infection among adults in 2017 was 64.4% and in 2018 70.2%, however, the observed increase in the number of infected individuals was not statistically significant (p0.05). The highest prevalence of H. pylori infection was observed in individuals 40 years of age (67.2%). Gender-related differences in the prevalence of Helicobacter pylori infection were revealed in individuals of 40 years and older. H. pylori infection in males of 40 years was 75.2%, against 65.5% in females of the same age (p0.05). In children of 4-16 years, the share of individuals with positive serological test with anti-H. pylori IgG reached 20.8%. All H. pylori infected children were above 9 years of age. Individuals with positive serological tests received consultation of a gastroenterologist, and on indications underwent additional examination with administration of eradication treatment. In patients with indefinite results the examination was repeated after a week and/or the presence of H. pylori antigen in feces was determined. Conclusion. The data obtained indicate a high level of infection with H. pylori in the adult population in the Ryazan region 65.6%. The incidence of detection of anti-H. pylori IgG in the population was maximal in individuals 40 years (67.2%).

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Frequency of Helicobacter Pylori Infection and Giardiasis in Children of Different Age Groups With Abdominal Pain and Dyspeptic Syndrome According to the Fecal Immunochromatographic Method

Cited by 2 publications

References 0 publications

Clinical and immunological peculiarities of parasitic infections in children with digestive system disorders in Western Ukraine

Clinical and immunological peculiarities of parasitic infections in children with digestive system disorders in Western Ukraine

Prevalence rate of Helicobacter pylori infection among population of Ryazan region

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