Frequency of fundal varices in cirrhotic patients with upper gastrointestinal bleed.

Malghani, Waseem Sarwar; Chaudhary, Farooq Mohyud Din; Din, Asim Tameez Ud; Chaudhary, Sana Mohyud Din; Din, Asma Tameez Ud

doi:10.29309/tpmj/2019.26.10.3164

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Treatment of hepatitis C virus is essential in halting the disease progression and preventing cirrhosis and its complications such as ascites, spontaneous bacterial peritonitis [22], encephalopathy, variceal bleeding [23,24], renal failure and increased mortality. Due to the high prevalence rates of hepatitis C in this area [10,25], eradication of this infection is of utmost importance.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Sofosbuvir, Daclatasvir and Ribavirin combination therapy in treatment naïve hepatitis C patients at tertiary care hospital of South Punjab

Umar

Gul

Chaudhary

et al. 2021

Preprint

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IntroductionHepatitis C has gradually become endemic in Pakistan, with infectivity rates one of the highest in the world. The emergence of direct acting antivirals (DAAs) has become a ray of sunshine in eradicating this menace from this region. The combination of sofosbuvir, daclatasvir and ribavirin (SOF/DACLA/RIBA) has had phenomenal success all over the world in eradicating this virus. Our study aims to see the effectiveness of this regime in this part of the world.MethodsAfter approval from the institutional review board (IRB), retrospective analysis of data of treatment naïve patients who have been treated with the above mentioned regimen was collected to assess the efficacy by calculating the sustained virological response (SVR) at 12 weeks after completion of therapy.ResultsData of 300 patients (172 females, 128 males) was collected. Mean age was 39.66 years. Majority (almost 90%) of patients were from District Multan Age range was from 18 years to 60 years. Eighty-three percent of the patients were non-cirrhotics, 15.7% had compensated cirrhosis, while only 1 % had decompensated cirrhosis. Out of the 300 patients, 291 patients had undetectable HCV RNA on polymerase chain reaction (PCR) at 12 weeks after completion of treatment, achieving SVR rates of 97%. There was no significant association of SVR rates with gender and age of patients.ConclusionThe combination of SOF/DACA/RIBA is highly efficacious for treatment of hepatitis C patients.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Sofosbuvir, Daclatasvir and Ribavirin combination therapy in treatment naïve hepatitis C patients at tertiary care hospital of South Punjab

Umar

Gul

Chaudhary

et al. 2021

Preprint

Self Cite

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Endoscopic findings in patients with persistent dyspepsia in a tertiary care hospital of south Punjab

Chaudhary

Gul

Hameed

et al. 2021

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Background: One of the most common clinical problem encountered by physicians in clinical practice is dyspepsia. This symptom has great impact on quality of life of patients. There are numerous causes of dyspepsia, organic as well as functional. Endoscopy is the diagnostic test of choice in these patients. Aim: The aim of our study was to see the endoscopic findings in patients with persistent dyspepsia. Methods: Retrospective analysis of data of patients who underwent Esophagogastroduodenoscopy (EGD) for persistent dyspepsia was collected and evaluated. Results: There were 495 patients in our study, 244 females and 251 males, with a mean age of 41 years. Almost half of the patients belonged to 21-40 years age group. The most common endoscopic finding in patients with persistent dyspepsia was gastritis (n=219, 44.2%), followed by normal endoscopy (n= 94, 19%), incompetent lower esophageal sphincter (n=67, 13.5%), gastric malignancy (n=48, 9.7%). Ulcer disease was found in just 15 patients (3%). Conclusion: Most common endoscopic finding in patients with persistent dyspepsia was gastritis followed by normal endoscopy. Key Words: dyspepsia, endoscopy

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Frequency of fundal varices in cirrhotic patients with upper gastrointestinal bleed.

Cited by 2 publications

References 13 publications

Efficacy of Sofosbuvir, Daclatasvir and Ribavirin combination therapy in treatment naïve hepatitis C patients at tertiary care hospital of South Punjab

Efficacy of Sofosbuvir, Daclatasvir and Ribavirin combination therapy in treatment naïve hepatitis C patients at tertiary care hospital of South Punjab

Endoscopic findings in patients with persistent dyspepsia in a tertiary care hospital of south Punjab

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