Frequency of dog erythrocyte antigen 1.1 expression in dogs from Portugal

Ferreira, Ricardo Artur Sanguinetti; Gopegui, Rafael Ruiz de; Matos, Augusto de

doi:10.1111/j.1939-165x.2011.00311.x

Cited by 25 publications

(52 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The probability of an Ibizan hound becoming sensitized following the first transfusion of blood that was neither cross-matched nor typed for DEA 1 was calculated using the following formula [5, 10]:

\begin{matrix} [\frac{(% DEA  1 negative \times % DEA  1 positive)}{100}] . \end{matrix}

…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island

Spada

Proverbio

Flórez³

et al. 2016

Veterinary Medicine International

View full text Add to dashboard Cite

The aims of this study were to evaluate the prevalence of Dog Erythrocyte Antigens (DEA) 1, 4, and 7 in Ibizan hounds, to compare the results with the prevalence of DEA in Spanish greyhounds, and to determine the risk of sensitization following the first transfusion of blood not typed for DEA 1 and the probability of an acute hemolytic reaction following a second incompatible transfusion using untyped DEA 1 blood. DEA 1, 4, and 7 status was determined in 92 Ibizan hounds. Results were compared with the previously reported prevalence in Spanish greyhounds. The risks of sensitization and of a hemolytic transfusion reaction were determined amongst Ibizan hounds and between Ibizan hounds and Spanish greyhounds. The prevalence of DEA 1, 4, and 7 was 75%, 98.9%, and 25%, respectively. There was a significantly higher expression of DEA 1 and 7 in Ibizan hounds than in Spanish greyhounds. The probability of sensitization of a recipient dog to DEA 1 with transfusions amongst Ibizan hounds was 18.5% and between Ibizan hounds and Spanish greyhounds was 13.7%. The probability of an acute hemolytic reaction in each group was 3.5% and 1.9%, respectively. There is a higher prevalence of DEA 1 and 7 in Ibizan hounds than in other sighthounds.

show abstract

\begin{matrix} [\frac{(% DEA  1 negative \times % DEA  1 positive)}{100}] . \end{matrix}

…”

Section: Methodsmentioning

confidence: 99%

“…The probability of the same dog developing an acute hemolytic reaction with a second incompatible transfusion using untyped blood from any other dog was calculated using the following formula [10]:

\begin{matrix} \frac{[(% DEA  1 negative \times % DEA  1 positive) \times % sensitization  for  the  first  transfusion]}{10,000} . \end{matrix}

…”

Section: Methodsmentioning

confidence: 99%

Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island

Spada

Proverbio

Flórez³

et al. 2016

Veterinary Medicine International

View full text Add to dashboard Cite

show abstract

“…Potential risk of sensitisation after a non-typed blood transfusion using blood from a galgo in a recipient of other breed was calculated by multiplying the frequency of DEA 1.1 negative blood in the control group and the frequency of DEA 1.1 positive blood in galgos (Novais and others 1999, Kessler and others 2010, Ferreira and others 2011). …”

Section: Methodsmentioning

confidence: 99%

“…DEA 1.1 is expressed in approximately 40–60 per cent of the general canine population. However, marked differences in DEA 1.1 frequencies among breeds and geographic locations have been reported (Novais and others 1999, van der Merwe and others 2002, Nottidge and others 2006, Gracner and others 2007, Hale and others 2008, Zubcic and others 2008, Iazbik and others 2010, Ergul Ekiz and others 2011, Ferreira and others 2011). …”

Section: Introductionmentioning

confidence: 98%

Prevalence of dog erythrocyte antigen 1.1 in galgos (Spanish greyhounds)

et al. 2014

View full text Add to dashboard Cite

Dog erythrocyte antigen (DEA) 1.1 is the most clinically important blood group in dogs, as negative recipients for this group may develop a life-threatening acute haemolytic transfusion reaction if they receive several DEA 1.1 positive blood transfusions. Due to their physical features, galgos are frequently used as blood donors in clinical practice, however, there are no published data regarding the prevalence of DEA 1.1 in this breed. Expression of DEA 1.1 was determined in 118 galgos and 88 dogs of other breeds being screened as potential blood donors, using an immunochromatographic cartridge typing kit (Quick Test DEA 1.1, Alvedia, Lyon, France). Of the total dogs, 53.4per cent (110/206) were positive for DEA 1.1. The prevalence of DEA 1.1 positive blood among our population of galgos and other-breed dogs were 51.7 per cent (61/118) and 55.7 per cent (49/88), respectively. Potential risk of sensitisation in a recipient of other breed following non-typed blood transfusion using blood from galgos was 22.9 per cent. Due to the clinical significance of DEA 1.1 and the high prevalence of this blood group in galgos of Spain, we strongly recommend blood-typing for this group before administering any blood transfusion using galgos as donors, as with transfusions from other commonly used breeds.

show abstract

“…Os resultados encontrados no presente trabalho quanto ao risco transfusional diferem de valores encontrados em investigados anteriores, nas quais a probabilidade de ser utilizado sangue incompatível quanto ao AEC 1.1 numa primeira transfusão variou de 7,2 a 25,3%, de acordo com as raças estudadas (ERKIL EQUIZ et al, 2011;FERREIRA;GOPEGUI;MATOS, 2011). Novais, Santana e Vicentin (1999) encontraram o risco de sensibilização na primeira transfusão de cerca de 4,4% e de 2,2% do mesmo animal receber sangue incompatível numa segunda transfusão, mas não houve divisão quanto às raças.…”

Section: Discussionunclassified

Estudo da frequência dos antígenos eritrocitários caninos 1, 1.1 e 7 e risco de transfusão incompatível em cães de diferentes raças e mestiços da região metropolitana da cidade de São Paulo-SP, Brasil

Souza

Stopiglia

Gomes

et al. 2014

Braz. J. Vet. Res. Anim. Sci.

View full text Add to dashboard Cite

ResumoO presente trabalho estudou a frequência dos grupos sanguíneos identificados como antígenos eritrocitários caninos (AEC) 1, 1.1 e 7 em cães da região metropolitana da cidade de São Paulo-SP, Brasil, e calculou o risco de administração de sangue incompatível tanto em uma primeira quanto em uma segunda transfusão. Para tanto, 300 cães não aparentados foram divididos igualmente em seis grupos de acordo com as raças: Pastor Alemão (PA); Rottweiler (R); Poodle (P); Cocker Spaniel Inglês (CS); raças definidas diversas (RDD) e mestiços (M). Foi avaliada a relação entre a frequência dos AEC e os grupos raciais. A frequência geral de AEC 1 na população foi de 71% (AEC 1.1 -53,35%) e houve variações de acordo com as raças: PA-32% (AEC 1.1 -20%), R-98% (1.1 -80%), P-76% (1.1 -54%), CS-84% (1.1 -50%), RDD-62% (1.1 -56%) e M-74% (1.1 -60%). A frequência geral de AEC 7 foi de 39,33% e não houve diferenças significativas entre as raças. O risco de um cão negativo para o AEC 1 receber sangue positivo foi de 0,6 a 66,6% em uma primeira transfusão e de 0,21 a 65,3% do mesmo cão receber sangue incompatível em uma segunda transfusão. O risco quanto ao AEC 7 foi de 23,86% na primeira transfusão e 9,4% numa segunda transfusão. Este trabalho concluiu que houve variação na frequência de AEC1 e AEC 1.1, mas não quanto ao AEC 7 entre raças. Esta variação na porcentagem de animais positivos quanto ao AEC 1 se refletiu na grande variação no risco de uso de sangue incompatível. Portanto, conhecer a frequência dos AEC na população tem impacto direto no manejo entre cães doadores e receptores, mas a utilização conjunta de teste de tipagem sanguínea e reação cruzada reduz a possibilidade de transfusão de sangue incompatível.Palavras-chave: Tipagem sanguínea canina. Cães. AEC. Risco transfusional. Medicina transfusional veterinária. AbstractIt was investigated the frequency of blood groups identified as Dog Erythrocyte Antigens (DEA) 1, 1.1 and 7 dogs in the metropolitan region of São Paulo-SP, Brazil, and calculated the risk of administering incompatible blood in both first and second transfusion. For both, 300 unrelated dogs were equally divided into six groups according to the breeds: German Shepherd (GS), Rottweiler (R) Poodle (P), Cocker Spaniel (CS); defined several races (DSR), mongrel dogs (M). It was evaluated the relationship between the frequency of AEC and racial groups. The overall frequency of DEA 1 in population was 71% (DEA 1.1 -53.35%) and there were variations according to the breeds: GS-32% (DEA 1.1 -20%), R -98% (1.1 -80%) P -76% (1.1 -54%), CS-84% (1.1 -50%), DSR-62% (1.1 -56%) and M -74% (1.1 -60%). The overall frequency of BCE 7 was 39.33%, and there were no significant differences between the breeds. The risk of a dog negative DEA receiving 1 positive blood was 0.6 to 66.6% in the first transfusion and 0.21 to 65.3% from the same animal dog receiving incompatible blood transfusion in a second. The risk of the DEA 7 was 23.86% in the first transfusion and 9.4% in a second transfusion. This study concluded that there...

show abstract

Frequency of dog erythrocyte antigen 1.1 expression in dogs from Portugal

Cited by 25 publications

References 9 publications

Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island

Prevalence of Dog Erythrocyte Antigens 1, 4, and 7 in Podenco Ibicenco (Ibizan Hounds) from Ibiza Island

Prevalence of dog erythrocyte antigen 1.1 in galgos (Spanish greyhounds)

Estudo da frequência dos antígenos eritrocitários caninos 1, 1.1 e 7 e risco de transfusão incompatível em cães de diferentes raças e mestiços da região metropolitana da cidade de São Paulo-SP, Brasil

Contact Info

Product

Resources

About