Frequency of Distal Sensory Polyneuropathy among Diabetics in Parakou in 2012

Abstract

Background: The distal sensory polyneuropathy (DSP) was more frequent among diabetics, although its determinant was not well known among diabetics in Benin. Objective: We aimed to assess the frequency of DSP and its determinants among diabetics at Parakou. Methods: It was a cross-sectional study carried out from 1 March to 31 August 2012 and included 336 diabetics followed at the diabetes unit of Parakou hospital. The diagnosis of DSP was based on DNS (Diabetic Neuropathy Score) criteria and other criteria. All data concerning the diabetes mellitus were recorded. We used Epi-Info and SPSS 16.0 software to perform analysis. Results: They were 187 females (56.0%) with the mean age of 54.9 ± 10.9 years. 298 patients fulfilled criteria for DSP; the overall prevalence of DSP was 88.7%. The main associated factors in multivariate analysis were treatment duration of diabetes more than 4 years: OR = 36.7 [4.0-336.9]; the elevated glycaemia: OR = 3.1 [1.4-7.1]; the activity with high income: OR = 0.2 [0.0-0.8]; the ethnicity: nagots/fon: OR: 3.7 [1.4-12.5]. Conclusion: Those results suggested the high frequency of DSP among diabetics at Parakou.

Peripheral Sensory Neuropathy and associated factors among adult diabetes mellitus patients in Bahr Dar, Ethiopia

“…Similar findings were observed in studies conducted in Brazil and India [25, 26], However no such association was observed in other studies conducted in India, Iran, Benin, Taiwan [10, 14, 20, 21] The reason behind might be physical exercise can increase micro-vascular circulation, prevent aging, boosts immune system, gives strength to muscle and cardiovascular system as well as physiological well-being of the body so as to negatively affect the occurrence of DPSN.…”

“…Our findings were also lower than the study done in USA (66.7%), Benin (88.7%) and Taiwan (71%) [19–21]. The differences in prevalence could possibly be due to differences in outcome tool and patient characteristics.…”

“…Unlike the present study, low education level, low income, ethnicity being black, presence of hypertension, and male gender were significantly associated with the incidence of DPSN in studies done in Iran, Benin, Bangladesh, Taiwan, and Ethiopia respectively [12, 18, 20, 21, 26]. The possible reason behind this might be the methodology of the study, study area, and difference in sample size of the study.…”

“…Which is imilar to findings reported in studies conducted in University of Alfenas, Brazil, Fasa University, Hamedan province, Iran, Ethiopia, Benin, USA, Nigeria respectively [5, 10, 14, 15, 21, 23, 24]. Aging is a well known risk factor for many non-communicable diseases including DM and increasing age is a risk factors for many neurological disorder, probably reflecting the limited regenerative capacity of the nervous system after any insult.…”

“…The study done in Benin used diabetic neuropathy score (DNS) tool and investigated only patients with neuropathic symptoms unlike the present study which investigated all symptomatic and asymptomatic diabetic patients with MNSI. Others studied patients with neurological signs [1, 22] and some studies also combined both neuropathic symptoms and neurological signs similar with this study [15, 17, 21]. Some studies included neurological complications of diabetes patients, motor, sensory and autonomic nerves whereas other authors combined both patients with foot ulcers and peripheral neuropathy [14, 17, 18].…”