Frequency of Cardiovascular Manifestation in Patients With Rheumatoid Arthritis

Kumar, Pardeep; Kalpana, Fnu; Khamuani, Manoj Kumar; Lohana, Sameer; Dembra, Suman; Jahangir, Maha; Anees, Faryal; Kumar, Besham

doi:10.7759/cureus.14631

Cited by 4 publications

(5 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cardiovascular manifestations are above all the severity of the disease and are very frequent [41]. Kumar et al [42] in Pakistan and Yao-Wei et al [43] in South Korea reported a frequency of 58.2% and 10.9% respectively. Sicca syndrome was also common; Bentaleb et al [30] reported a prevalence of 81.9% and Uribe-Reina et al [28] 19.7%.…”

Section: Discussionmentioning

confidence: 98%

Comorbidities and extra-articular manifestations of Rheumatoid arthritis in sub-Saharian Africa

ALASSANI¹,

DOVONOU²,

WANVOEGBE³

et al. 2023

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

Rheumatoid arthritis is a systemic auto-immune disorder that preferentially affects the joints. Extra-articular manifestations and comorbidities observed during rheumatoid arthritis are multiple and frequent. They are the cause of high morbidity and mortality in this population and make rheumatoid arthritis serious. Systematic screening for the extra-articular manifestations and comorbidities is therefore necessary in order to optimize its management in affected subjects. The various studies carried out on rheumatoid arthritis in developing countries have explored less the extra-articular manifestations as well as the comorbidities. This work reviews the literature on the extra-articular manifestations as well as the comorbidities encountered in subjects with rheumatoid arthritis in Sub saharia Africa in order to draw the attention of the nursing medical staff to their extent in order with a view to systematic screening and treatment.

show abstract

Section: Discussionmentioning

confidence: 98%

Comorbidities and extra-articular manifestations of Rheumatoid arthritis in sub-Saharian Africa

ALASSANI¹,

DOVONOU²,

WANVOEGBE³

et al. 2023

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

show abstract

“…Pericarditis associated with rheumatoid arthritis is not necessarily related to the severity of joint symptoms. In patients with rheumatoid arthritis who have extra-articular symptoms predominantly, it has been suggested that it is difficult to distinguish rheumatoid pericarditis from various other diseases [7,9].…”

Section: Discussionmentioning

confidence: 99%

“…This case of pericarditis in a patient with rheumatoid arthritis who had clinically mild joint symptoms suggests the importance of monitoring the daily symptoms in these patients. In general, complications of rheumatoid arthritis-associated pericarditis are related to the disease activity of rheumatoid arthritis [7]. When a patient with poorly controlled rheumatoid arthritis complains of symptoms, such as chest pain, dyspnea, and lower leg edema, it is necessary to proceed with a systematic and detailed evaluation to rule out pericarditis [10].…”

Section: Discussionmentioning

confidence: 99%

“…Various factors, including high levels of inflammatory proteins, such as C-reactive protein, and erythrocyte sedimentation rate, are associated with the onset of pericarditis among patients with rheumatoid arthritis [6]. In addition, elevated rheumatoid factor and anti-citrullinated peptide antibodies are considered risk factors for pericarditis [7]. To prevent the onset of pericarditis, it is necessary to control the disease activity of rheumatoid arthritis at an early stage.…”

Section: Introductionmentioning

confidence: 99%

“…To prevent the onset of pericarditis, it is necessary to control the disease activity of rheumatoid arthritis at an early stage. Therefore, the complication of pericarditis-associated rheumatoid arthritis could be related to the disease severity of rheumatoid arthritis, and individuals with more severe rheumatoid arthritis are at a greater risk of developing pericarditis [5,7]. However, in many cases, cardiac tamponade does not occur and the condition is relieved by continued drug treatment [8].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pericarditis With Cardiac Tamponade Mimicking Yellow Nail Syndrome in a Patient With Rheumatoid Arthritis and a Paucity of Joint Symptoms

Tokonami¹,

Ohta²,

Tanaka³

et al. 2022

Cureus

View full text Add to dashboard Cite

Pericarditis is a cardiac disease that commonly manifests with rheumatoid arthritis, and its complications are related to rheumatoid arthritis disease activity. The diagnosis can be complicated in patients with multiple extra-joint complications of rheumatoid arthritis. We report a case of pericarditis in an 82-year-old woman with few joint symptoms who was admitted to the hospital due to worsening edema of the lower legs and dyspnea, which progressed to cardiac tamponade. The patient presented with gradual onset of edema of both lower limbs and bilateral pleural effusion and was initially diagnosed with yellow nail syndrome. Ultimately, the patient was diagnosed with rheumatoid pericarditis due to a rapid increase in pericardial effusion. She was treated with non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine; however, the symptoms were progressive and required pericardiocentesis. After pericardiocentesis, the patient responded well to NSAIDs and colchicine, and systemic edema was relieved. This case highlights the fact that pericarditis associated with rheumatoid arthritis is not necessarily related to the severity of joint symptoms. Moreover, it can be difficult to differentiate pericarditis from multiple other diseases, such as yellow nail syndrome, in patients with rheumatoid arthritis who mainly have extra-articular symptoms.

show abstract

Association between Diabetes and Rheumatoid Arthritis: A Systematic Literature Review

Okais¹,

Fayad²,

Baddoura³

et al. 2022

TORJ

View full text Add to dashboard Cite

Objective To examine the risk of diabetes mellitus (DM) in patients with rheumatoid arthritis (RA) and whether the risk is related to conventional risk factors, RA disease activity, and treatment. Methods A systematic literature review (SLR) query was conducted using specified MeSH terms, searching PubMed and EMBASE databases from inception to March 2020. Both cohort or case-control design studies assessing the incidence or prevalence of DM in RA patients were included. Results Of the 1948 articles, 43 peer-reviewed observational studies were selected. A high degree of heterogeneity in study design and reporting was observed, precluding final conclusions. Based on the studies included, it was observed that DM prevalence ranged between 1% and 20% in RA patients, which was similar to controls (1–29%). The cumulative incidence of DM in RA patients ranged between 1.3% and 11.7% over different time frames. DM incidence rates in patients with RA per 1000 person-years ranged from 5.2 to 16.7. RA patients may be at higher risk of DM, particularly among those receiving glucocorticoids (GC), while patients on hydroxychloroquine and biological disease-modifying anti-rheumatic treatments (DMARDs) may be at lower risk. Conclusion DM incidence may be increased in patients with RA as a result of more concomitant traditional risk factors and GC exposure. It is unclear whether biologics may have a true protective effect or provide a GC-sparing effect. High-quality studies in large cohorts of RA patients with appropriate adjustment for covariates are warranted to fully investigate the interplay between DM and RA.

show abstract

Frequency of Cardiovascular Manifestation in Patients With Rheumatoid Arthritis

Cited by 4 publications

References 16 publications

Comorbidities and extra-articular manifestations of Rheumatoid arthritis in sub-Saharian Africa

Comorbidities and extra-articular manifestations of Rheumatoid arthritis in sub-Saharian Africa

Pericarditis With Cardiac Tamponade Mimicking Yellow Nail Syndrome in a Patient With Rheumatoid Arthritis and a Paucity of Joint Symptoms

Association between Diabetes and Rheumatoid Arthritis: A Systematic Literature Review

Contact Info

Product

Resources

About