Frequency-modulated timer regulates torpor–arousal cycles during hibernation in distinct small mammalian hibernators
Shingo Gibo,
Yoshifumi Yamaguchi,
Elena O. Gracheva
et al.
Abstract:Hibernation allows mammals to endure harsh seasons by reducing their basal metabolism and body temperature (Tb) to minimize energy expenditure. During hibernation in small animals such as Syrian hamsters and 13-lined ground squirrels, Tb decreases to an ambient level ( < 5 °C) and remains constant for days to weeks in a physiological condition termed deep torpor. Torpor is interrupted by periods of arousal, during which Tb recovers to a euthermic level (approximately 37 °C), and these torpor–arousal cycles … Show more
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