Frequency, Etiology and Immediate Outcome of Children Admitted to Pediatric Intensive Care Unit (Picu) With Convulsive Status Epi Lepticus in Kashmir North India

Jan, Muzafar; Naik, Suhail; Ali, Sartaj; Rafiq, Waseem; Kachroo, Aliya; Maqbool, Mudasir

doi:10.14260/jemds/2015/1574

Cited by 2 publications

(5 citation statements)

References 10 publications

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“…A study of Jan et al . [ 14 ] supports our finding with a male-to-female ratio of 1.35:1 in their study. In addition, our results are consistent with many of the Indian studies which have found male preponderance for SE.…”

Section: Discussionsupporting

confidence: 92%

“…Jan et al . [ 14 ] also found GTCS as the most common type of seizure with 85% of their patients having this type of seizure but found a different profile for other types of seizure than our study with 10% of their patients having myoclonic seizures, 4% with tonic type and 0.83% with CPS type. Although there is some variation, majority of patients in both these studies were having the same type of seizure.…”

Section: Discussioncontrasting

confidence: 69%

“…This is in coherence with the study of Jan et al . [ 14 ] who found about 70% of their patients below 6 years of age. Our results are also consistent with many Indian studies which have shown predominant involvement of younger age group.…”

Section: Discussionmentioning

confidence: 99%

“…Jan et al . [ 14 ] found remote symptomatic cause in 30% and prolonged febrile convulsion in 23.3% while 18% of their patients had acute symptomatic etiology. Their results are inconsistent with our study, but they stated in their study that their results are in discordance with most of the previous studies.…”

Section: Discussionmentioning

confidence: 99%

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Sociodemographic Profile, Semiology, and Etiology of Patients with Status Epilepticus: A Study from a Tertiary Care Hospital in North India

Qadir

Wani

Bhat

2018

Journal of Neurosciences in Rural Practice

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Background and Objectives:Despite advance in treatment of status epilepticus (SE), a major neurological emergency, it is still associated with mortality and morbidity. The objective of our study was to estimate sociodemographic profile, semiology, and etiology in the children with SE admitted in pediatric intensive care.Materials and Methods:Children between 1 month and 18 years with continuous seizure activity of >5 min or two or more sequential seizures without full recovery of consciousness between seizures, admitted in the Pediatric Intensive Care Unit of the Department of Pediatrics, Government Medical College, Srinagar, were included in the study. A semi-structured tool was designed to record the sociodemographic details. Detailed history, clinical examination, and investigations (including neuroimaging as and when needed) were used to determine the type of seizure and etiology.Results:A total of 51 patients were included in our study. Most of the patients were <5 years with 47.10% in 1–5 years’ age group and 43.10% in >1-year age group. Males (60.80%) outnumbered females. Thirty-nine patients (76.47%) belonged to “known” or “symptomatic” group with 35 (68.60%) of them presenting with SE as their fresh seizure. Thirty-nine (76.47%) of our patients had generalized tonic–clonic seizure (GTCS) type of SE.Conclusion:Most of the children (90%) were below the age of 5 years with male predominance. Most of the patients had SE as their first seizure without prior history of seizures with GTCSs was the most frequent seizure type.

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Section: Discussionsupporting

confidence: 92%

Section: Discussioncontrasting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Sociodemographic Profile, Semiology, and Etiology of Patients with Status Epilepticus: A Study from a Tertiary Care Hospital in North India

Qadir

Wani

Bhat

2018

Journal of Neurosciences in Rural Practice

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“…A systematic review of 63 studies conducted worldwide showed that mortality among children admitted to PICU with status epilepticus is 5–8% [ 19 ]. Indian studies have reported higher rates of 16.7% from Kashmir [ 20 ], 30% from Delhi [ 12 ] and 31.4% from Bihar [ 16 ]. This contrasts with our study which had a mortality rate of 8.9%.…”

Section: Discussionmentioning

confidence: 99%

A study of critically ill children presenting with seizures regardless of seizure duration admitted in the PICU of a tertiary hospital in India

Amonkar¹,

Revathi²,

Gavhane³

2020

Epilepsy & Behavior Reports

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Our aim was to study the clinical profile, immediate outcome and risk factors associated with poor outcome in critically ill children presenting with seizures requiring PICU admission. As seizures lasting 10 min or more can potentially cause brain damage, we included all children regardless of seizure duration. The records of 157 children aged 1 month to 16 years admitted in the PICU at a tertiary hospital in India with seizures as the presenting symptom during a three-year period were studied retrospectively. Median age of patients was 4 years. 34 (21%) had pre-existing epilepsy and 33 (21%) had previous developmental delay/neuro-deficit. Seizure duration was > 30 min in 75 (47.7%) and 56 (35.6%) required the use of more than 2 antiseizure drugs. 101 (64%) had acute symptomatic seizures, 28 (17%) remote symptomatic and 27 (17.1%) had unknown cause. New onset neurological deficit was seen in 18 (15.6%) and 14 (8.9%) died. Young age, high PEWS score at presentation, prolonged/recurrent seizures, CNS infection, need for multiple antiseizure drugs and ventilation/pressor use were risk factors for poor outcome. Neurological outcome and survival of children in our study were good. Further all-inclusive studies irrespective of seizure duration are needed to obtain a complete picture of critical children presenting with seizures.

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Frequency, Etiology and Immediate Outcome of Children Admitted to Pediatric Intensive Care Unit (Picu) With Convulsive Status Epi Lepticus in Kashmir North India

Cited by 2 publications

References 10 publications

Sociodemographic Profile, Semiology, and Etiology of Patients with Status Epilepticus: A Study from a Tertiary Care Hospital in North India

Sociodemographic Profile, Semiology, and Etiology of Patients with Status Epilepticus: A Study from a Tertiary Care Hospital in North India

A study of critically ill children presenting with seizures regardless of seizure duration admitted in the PICU of a tertiary hospital in India

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