Frequency-Doubling Technology Perimetry for Detection of the Development of Visual Field Defects in Glaucoma Suspect Eyes

Abstract

IMPORTANCE While standard automated perimetry (SAP) remains the reference standard for evaluation of visual field (VF) defects in glaucoma, this study demonstrates that frequency-doubling technology (FDT) perimetry is effective in monitoring visual field progression and may detect the onset of visual field defects earlier than SAP.OBJECTIVES To compare detection of the development of VF defects, rate of change of VF loss, and risk factors for progression between SAP and matrix FDT perimetry in glaucoma suspect and ocular hypertensive eyes. DESIGN, SETTING, AND PARTICIPANTSA total of 113 glaucoma suspect and ocular hypertensive eyes from 76 patients with normal SAP and FDT perimetry results at baseline were prospectively followed up for SAP and FDT perimetry testing at approximately 4-month intervals for 30 months or longer. Patients were consecutively enrolled and followed up from

How to detect progression in glaucoma

“…In glaucoma suspects, Meira-Freitas et al (2014) reported that faster rates of increase of FDT pattern deviation were related to higher chance of progression in SAP, and Liu et al (2014b) reported that approximately the same number of suspects developed reproducible defects in FDT or in SAP. In glaucoma patients, Liu et al (2014a) identified more progressing patients with FDT than SAP; however, Redmond et al (2013) identified more progressing patients with SAP than FDT. While some studies suggest that FDT may be useful to evaluate progression of glaucoma functional damage, further research is required to better assess its additional value to SAP, before recommending frequent clinical use.…”

Comparison of Standard Automated Perimetry, Short-Wavelength Automated Perimetry, and Frequency-Doubling Technology Perimetry to Monitor Glaucoma Progression

“…They also found faster rates of FDT PSD change in glaucoma suspect and ocular hypertensive eyes compared to SAP. 33 These studies, however, compared the tests directly, without consideration for the differences in scales. Our results are consistent with those reported by Redmond et al, 31 who did not find evidence that FDT is more sensitive than SAP using permutation of PLR.…”

“…29 Although these properties may provide potential advantages for FDT in monitoring glaucomatous progression, the results from several recent longitudinal studies do not conclusively show an advantage for FDT compared to SAP. 16,30–33 …”

Evaluation of Visual Field Progression in Glaucoma

“…Although controversial, there is increasing evidence of the utility of frequency doubling technology perimetry (FDT) for the early detection of glaucoma [22,23]. There are no established criteria or commercially available tools for the detection of FDT VF progression.…”