Frequency Distribution Of Sperm Counts In Fertile And Infertile Males

Zukerman, Zvi; Rodriguez‐Rigau, Luis J.; Smith, Keith D.; Steinberger, Emil

doi:10.1016/s0015-0282(16)42975-4

Cited by 167 publications

(64 citation statements)

References 3 publications

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“…On the basis of sperm density, two groups of patients were easily identi fied in this report: first, patients whose sperm counts are less than 10 million/ml and constitute the bulk (81 %) of the patient population, and second those with sperm concentrations over 10 million ml (19%). This distribu tion pattern differs remarkably from those of Zukerman et al [4] and Macleod and Gold [ 1 ] (table II).…”

Section: Discussioncontrasting

confidence: 57%

See 1 more Smart Citation

Semen Features of 596 Truly Infertile Men

Osegbe¹,

Amaku²

1987

Eur Urol

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Section: Discussioncontrasting

confidence: 57%

“…The results of this study are compared largely with those of Macleod and Gold [1], and Zukerman et al [4]. References, where necessary, are also made to other authors.…”

Section: Introductionmentioning

confidence: 58%

Semen Features of 596 Truly Infertile Men

Osegbe¹,

Amaku²

1987

Eur Urol

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“…The low sperm concentration noted in 5% of semen samples from men classified as fertile because they had a pregnant partner conforms to what was published in the 1970s by David et al [8], Eliasson [7], MacLeod and Wang [9], Smith et al [10], Sobrero and Rehan [11], Zuckerman et al [12], van Zyl et al [13], and others. Maybe the lower reference limit presented by WHO together with these supporting references can finally overthrow the 20 million mL -1 paradigm.…”

Section: Number Of Spermatozoasupporting

confidence: 87%

Semen analysis with regard to sperm number, sperm morphology and functional aspects

Eliasson¹

2010

Asian J Androl

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The new World Health Organization (WHO) Manual for Semen Analysis contains several improvements. One is that the 20 million spermatozoa per mL paradigm has been ousted in favour of proper calculations of lower reference limits for semen from men, whose partners had a time-to-pregnancy of 12 months or less. The recommendation to grade the progressive motility as described in the third and fourth editions of the WHO manual was not evidence-based, and WHO was therefore motivated to abandon it. However, the new recommendation is not evidence-based either, and it is difficult to understand the rational for the new assessment. It may have been a compromise to avoid returning to the rather robust system recommended in the first edition (1980). The unconditional recommendation of the 'Tygerberg strict criteria' is not evidence-based, and seems to be the result of an unfortunate bias in the composition of the Committee in favour of individuals known to support the 'strict criteria' method. This recommendation will have negative effects on the development of andrology as a scientific field. Given the importance of the WHO manual, it is unfortunate that the recommendations for such important variables, as motility and morphology, lack evidence-based support.

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“…Moreover, none have employed a control group. Most published reports involve males after orchiopexy [4, 5, 6, 7, 8, 9, 10], one included those having had hormonal treatment [11]. The sample sizes are small, and only about half were married thus making it difficult to determine paternity rates.…”

Section: Discussionmentioning

confidence: 99%

Fertility after Unilateral Cryptorchidism

2001

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Objective: To further evaluate whether fertility is decreased among a cohort of men with previous unilateral cryptorchidism as compared with a control group of men. Subjects and Methods: Formerly unilateral cryptorchid men who had undergone orchiopexy between the years of 1955 and 1975 at the Children’s Hospital of Pittsburgh and a control group of men who were matched for age of an unrelated surgery at the same institution were evaluated by review of medical records and by completion of a questionnaire. 359 previously cryptorchid men were identified as having attempted paternity. Of these men, 320 had information concerning preoperative testicular location and 163 for preoperative testicular size. 106 of these men had levels of testosterone, inhibin B, FSH, and LH measured, while 95 of the men had semen analyses. Results: Among men who had attempted paternity, there was no statistical difference in success of paternity between the previously unilateral group (89.7%) and the control group (93.7%). There was no difference in the mean time to conception (7.1 ± 0.7 months for the unilateral group vs. 6.9 ± 2.3 for the control group). Within the unilateral group in regard to success at paternity, no difference was found compared with the age of orchiopexy, preoperative testicular location, or preoperative testicular size. Inhibin B levels were lower among the unilateral group. FSH, LH, testosterone, sperm density, motility and morphology were not different, but considerable variation was noted within the cryptorchid group. Conclusions: In this continued evaluation of a cohort of previously cryptorchid men who had undergone unilateral orchiopexy, paternity does not appear to be significantly compromised after unilateral cryptorchidism. Unilateral cryptorchidism appears to be one of several factors contributing to infertility, similar to those found in the general population. No correlation was found between success at paternity and the age of orchiopexy, preoperative testicular size or preoperative testicular location. Inhibin B levels were lower while FSH, LH, T and sperm parameters did not differ.

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Frequency Distribution Of Sperm Counts In Fertile And Infertile Males

Cited by 167 publications

References 3 publications

Semen Features of 596 Truly Infertile Men

Semen Features of 596 Truly Infertile Men

Semen analysis with regard to sperm number, sperm morphology and functional aspects

Fertility after Unilateral Cryptorchidism

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