Frequency Distribution of ABO/Rh Blood Group Systems in Breast Cancer, Yazd, 2007 - 2013

Abstract

Background:The various studies related to different aspects of breast cancer has or is being carried out all over the world, but the breast cancer developing risk factors in patients and high-risk people have not been well understood yet. The ABO/Rh systems blood group role as a factor increasing risk to getting some pathology has proven. So the survey of probable association between ABO/Rh systems blood group and breast cancer can be useful. Patients and Methods:This cross-sectional study included 197 women with breast cancer who referred to either Yazd Shahid Sadoughi hospital or Dr. Mortaz hospital during six years (2007 -2013) because of diagnosis or treatment. The patient's demographic and clinical data were extracted and evaluated from their clinical documents. Results: During 6 years, 375 reports of breast cancer were registered in 2 hospitals totally, that only data of 197 reports can be surveyed. The mean and limit of patient's age were 44 ± 5.3 years and 17 -70 years respectively. Most patients (93.4%) have Rh + blood group system. Blood type A + was the most prevalent among patients. Then O + and B + was the most which their frequency distribution was 21.4% (42) and 9.1% (18) respectively. The least frequency distribution of this blood group system was related to AB + which is observed in only 4% (8) of patients. Conclusions: Blood type A + has the most association with breast cancer according to the findings this article and can be used as a paraclinical marker in treatment and consulting of patients and high-risk people.

Study of the Relationship between ABO Blood Group Types and Breast Cancer and Cervix Cancer in Khuzestan Province, Iran

“…However, in a study conducted by R. Dixit et al, the distribution of ABO blood groups was B, O, A, and AB respectively 23 . In some studies, distribution was A, O, B, and AB Also, the Neelima Kumari et al reported A, B, O, and AB respectively 8 , 24 - 29 . However, a study reported A, B, O, and AB as ABO blood group distribution in breast cancer respectively and in another study, the distribution was O, A, B, and AB respectively 6 , 7 , 17 .…”

“…Gates et al reported that ABO blood groups have no relationship with breast cancer 17 , 23 , 24 . Nevertheless, recent studies have shown that blood group A is associated with breast cancer 6 - 8 , 10 , 26 , 27 , 29 . Also, a study in Turkey on 3944 breast cancer patients indicated that there was no significant difference between ABO blood group and grade, type, stage, and hormonal status of breast cancer 24 .…”

A Study of Association of ABO Blood Group types with Cancer Risk

“…In the present study, data from 243 number of cases and 250 controls, we found significant associations of blood group A with increased risk of Cancer in Eastern (U.P.). Studies across the word has shown association of blood group A with, Breast Cancer (18)(19)(20)(21), pancreatic cancer (22)(23)(24)(25), liver Cancer (26) gastric and lung Cancer (27,28,29,32,33,34) risk. Data from a these studies have shown that blood group A is associated with breast cancer, liver and pancreatic cancer, and lung cancer risk.…”

The Relationship between ABO Blood Groups, Rhesus Factor and Breast Cancer

“…Shiryazdi et al, [7] and Meo et al, [11] reported that frequency distribution numbers of women developed breast cancer with Rh-were less than numbers patients with Rh+. Also, Prakash et al, [3] reported that most of the respondents had Rh positive with breast cancer and was also found to be insignificant.…”

“…It is a life threatening disease among young premenopausal women affecting their sexuality, femininity, body image, and maternal issues following mastectomy may lead the women to face psychiatric co-morbidity [3]. It is the second leading cause of cancer deaths in women [5][6][7][8], affecting more than 2 million females each year. In 2018, breast cancer took the lives of 627,000 women, accounting for 15% of all cancer deaths among females [8,9].…”