Frequency and reason for reoperation following non-invasive expandable endoprostheses: A systematic review

Lex, Johnathan R.; Adlan, Amirul; Tsoi, Kim; Evans, Scott; Stevenson, Jonathan

doi:10.1016/j.jbo.2021.100397

Cited by 4 publications

(5 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous reports suggested that infection and local recurrence are the main reasons for failure 25,26 . The more specific types of implant failure consisted of insufficient maximal prosthesis lengthening; premature extension failure; prosthesis fracture; bushing or articulation wear 24 . In our study, only one patient had an infection.…”

Section: Effect Of Expandable Prosthesismentioning

confidence: 44%

“… 25 , 26 The more specific types of implant failure consisted of insufficient maximal prosthesis lengthening; premature extension failure; prosthesis fracture; bushing or articulation wear. 24 In our study, only one patient had an infection. Lower prosthesis complication rates reduced the risk of second intervention before replacement with a permanent prosthesis.…”

Section: Effect Of Expandable Prosthesismentioning

confidence: 55%

“…When placed at the center of a rotating electromagnetic field, implant was extended. The overall implant revision rate was 46.2% 24 …”

Section: Effect Of Expandable Prosthesismentioning

confidence: 95%

“…The overall implant revision rate was 46.2%. 24 We present an expandable prosthesis that restores defection of bone preserves the unaffected growth plate, and achieves adequate lengthening of the extremity. Small anatomic size is also the elementary factors in immature patients.…”

Section: Effect Of Expandable Prosthesismentioning

confidence: 99%

See 3 more Smart Citations

Neoadjuvant Chemotherapy and Expandable Prosthesis Reconstruction to Treat Osteosarcoma around the Knee in Children

Huang

Cheng

et al. 2022

Orthopaedic Surgery

View full text Add to dashboard Cite

Objective: Survival and reconstruction in osteosarcoma is quite challenging. The study aimed to investigate the prognosis in patients treated with neoadjuvant chemotherapy and determine the clinical outcomes of expandable endoprosthesis reconstruction in children. Methods:From January 2009 to December 2014, we retrospectively analyzed 29 skeletally immature children (mean age, 10.5 years; range, 6-15 years) with osteosarcoma around the knee. Of the 29 patients who underwent neoadjuvant chemotherapy and limb salvage surgery, an expandable prosthesis was implanted for reconstruction. No patients were missed during follow-up. The evaluation index involved follow-up time, complication, functional results, and lengthening procedures. The survivorship and recurrence were assessed by GraphPad Software, and the function was evaluated by the Musculoskeletal Tumor Society (MSTS) scoring system.Results: A mean follow-up time was 8.9 years (range, 6-12 years), and the overall 5-year survival was 89.1% based on Kaplan-Meier analysis. Three patients suffered a relapse and one underwent amputation. Lung metastasis developed in one patient. At 6 months after the operation, patients had a mean MSTS score of 27 points (range, 24-29). Two patients underwent revision surgery, one for implant infection and one for aseptic loosening. Prognosis is correlated with alkaline phosphatase change after treatment.Conclusions: Chemotherapy scheme and limb salvage can achieve high survival rates. This expandable prosthesis was associated with good function and low complication rates. The character of expandability could be a method to overcome discrepancies in the growth period.

show abstract

Section: Effect Of Expandable Prosthesismentioning

confidence: 44%

Section: Effect Of Expandable Prosthesismentioning

confidence: 55%

“…When placed at the center of a rotating electromagnetic field, implant was extended. The overall implant revision rate was 46.2% 24 …”

Section: Effect Of Expandable Prosthesismentioning

confidence: 95%

Section: Effect Of Expandable Prosthesismentioning

confidence: 99%

See 2 more Smart Citations

Neoadjuvant Chemotherapy and Expandable Prosthesis Reconstruction to Treat Osteosarcoma around the Knee in Children

Huang

Cheng

et al. 2022

Orthopaedic Surgery

View full text Add to dashboard Cite

show abstract

“…The first-generation lengthening prosthesis was designed by Dr. Scales and Stanmore in 1976. This prosthesis requires open surgery, which entails significant trauma, causing considerable discomfort, especially for patients who require multiple lengthening procedures ( Lex et al, 2021 ). A related study indicates that the infection of the prosthesis and postoperative complications, such as loosening of the prosthesis, is relatively high ( Schindler et al, 1997 ).…”

Section: Discussionmentioning

confidence: 99%

A novel non-invasive electromagnetic extendable intercalary endoprosthesis: a proof-of-concept study

Huang,

Yang,

et al. 2024

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Introduction: Femur and tibia are the most commonly affected sites for primary malignant bone tumors in children. The wide resection of the tumor frequently requires the physis to be resected. The normal growth of the unaffected limb will result in a significant limb length discrepancy at skeletal maturity. To compensate for this resulting LLD, different generations of extendible endoprostheses have been developed. Non-invasive extendable prostheses eliminate the need for surgical procedures and general anesthesia, enabling gradual and painless lengthening. Currently available non-invasive extendable prostheses focus on joint reconstruction, and no case series analysis of intercalary non-invasive extendable prosthesis has been reported. Therefore, we have designed a novel non-invasive electromagnetic extendable intercalary endoprosthesis.Methods:In vitro mechanical experiments and in vivo animal experiments were conducted.Results:In vitro experiments have confirmed that the prosthetics can extend at a constant rate, increasing by 4.4 mm every 10 min. The average maximum extension force during prosthetic elongation can reach 1306N. In animal in vivo experiments, the extension process is smooth and non-invasive, and the sheep is in a comfortable state.Discussion: The in vitro and in vivo animal studies provide evidence to support the extension reliability, laying the foundation for future large-scale validation experiments.

show abstract

Complications after limb salvage surgeries for musculoskeletal malignancies: 10-year experience of the main sarcoma center in Bulgaria

Ivanov,

Patrikov

2024

View full text Add to dashboard Cite

Introduction: Limb salvage surgery is currently the most frequently used treatment option in Bulgaria for individuals with musculoskeletal malignancies. Clinical data about complications from these procedures is limited in the country, with only a few studies currently available. Aim: The aim of our study is to analyze complication rates and patterns in Bulgarian patients treated with limb salvage surgery for musculoskeletal malignancies. Materials and methods: Our series consist of a retrospective review of 43 patients with musculoskeletal malignancies, who underwent limb salvage surgeries at Boycho Boychev University Orthopedic Hospital in Sofia, Bulgaria, over a period of 10 years. For staging, we used the AJCC and Enneking’s staging systems for malignant musculoskeletal tumors. Functionality was assessed with the MSTS system. Assessment of complications was done with a modified Clavien-Dindo classification for surgical complications and Henderson’s classification of failure of limb salvage after reconstructive surgery. Results: The mean follow-up time for the series is 40 months (range 12 to 120 months). At the current follow-up, the overall survival rate for the series is 72%. The overall complication rate for the series is 72% and the surgical revision rate is 46.5%. Of the encountered complications, 84% were classified as grade Ⅲb using the Clavien-Dindo classification. Conclusion: Bulgarian patients treated with limb salvage for musculoskeletal malignancies have high complication rates, with no clear prevalence between mechanical and non-mechanical complication patterns. Many of the encountered complications are severe and require additional surgical management.

show abstract

Frequency and reason for reoperation following non-invasive expandable endoprostheses: A systematic review

Abstract: Highlights Implant failure is the most common reason for revision of growing prostheses. Maximum prosthesis growth with a residual LLD is the most common mode of failure. Functional outcomes are good, but 1/ 5 patients have a persistent LLD over 2 cm.

Cited by 4 publications

References 60 publications

Neoadjuvant Chemotherapy and Expandable Prosthesis Reconstruction to Treat Osteosarcoma around the Knee in Children

Neoadjuvant Chemotherapy and Expandable Prosthesis Reconstruction to Treat Osteosarcoma around the Knee in Children

A novel non-invasive electromagnetic extendable intercalary endoprosthesis: a proof-of-concept study

Complications after limb salvage surgeries for musculoskeletal malignancies: 10-year experience of the main sarcoma center in Bulgaria

Contact Info

Product

Resources

About