Frequency and Outcome of Hepatic Arterial Thrombosis in Recipients of Living Donor Liver Transplantation

Ullah, Kaleem; Dogar, Abdul Wahab; Uddin, Shams; Hasnain, Syed; Bilal, Ahmad; Ghaffar, Abdul

doi:10.29271/jcpsp.2021.08.897

Cited by 7 publications

(6 citation statements)

References 18 publications

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“…2,10 Conventionally, the graft artery is anastomosed with the recipient's native HA. 9 In situations of inadequate hepatic arterial flow, various other transposed arteries can be utilized for HAR. [4][5][6][7][8] Literature had shown variable results regarding the utilization of the RGE artery for HAR.…”

Section: Discussionmentioning

confidence: 99%

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Splenic artery transposition for hepatic arterial supply in living donor liver transplantation

et al. 2022

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Objective: To determine the safety and outcome of splenic artery(SA) transposition in extra-anatomic hepatic arterial reconstruction (HAR) in living donor liver transplantation(LDLT). Methods: We retrospectively compared the outcome of the ten liver recipients who underwent HAR with the transposed splenic artery (SA group) with a matched cohort of 40 recipients who underwent HAR with the standard hepatic artery (HA group) between March, 2019 and December, 2020 at liver transplantation department, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Pakistan. The comparison of recipients’ and donor demographics, operative and graft characteristics, post-operative labs, Doppler ultrasound(USG) findings, and complications, along with 30-day mortality, and 1-year survival were reported for both groups. Results: The mean age of patients in the SA group was 42.80±7.510 and in the HA group was 43.73±8.171 years. The common indication of LDLT was viral hepatitis in both groups. The operative duration was longer in the SA group (597.50±41.3156 min) than in the HA group (530.75±66.502 min) with a significant p-value= 0.004. Similarly, blood loss was also more in the SA group (1635±226.139 ml) than in the HA group (1477.50±270.316 ml) (p-value= 0.096). The incidence of biliary and vascular complications, early allograft dysfunction, acute cellular rejection, 30-day mortality, and 1-year survival were comparable in both groups. Post-operatively splenectomy was not needed in any SA group recipients. Conclusion: The SA is easily approachable, suitable, and safe for HAR in the difficult situation of hepatic arterial flow inadequacy during LDLT due to its appropriate length, and good blood flow. doi: https://doi.org/10.12669/pjms.39.1.6351 How to cite this: Ullah K, Dogar AW, Shams-ud-Din, Bilal H. Splenic artery transposition for hepatic arterial supply in living donor liver transplantation. Pak J Med Sci. 2023;39(1):---------. doi: https://doi.org/10.12669/pjms.39.1.6351 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

“…Adequate arterial flow is mandatory for a successful LT outcome. 9 While deficient arterial flow causes graft dysfunction, biliary complications, and graft failure. 2 , 10 Conventionally, the graft artery is anastomosed with the recipient’s native HA.…”

Section: Discussionmentioning

confidence: 99%

Splenic artery transposition for hepatic arterial supply in living donor liver transplantation

et al. 2022

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“…Living donor liver transplantation (LDLT) is an established alternative to deceased donor transplantation [ 1 , 2 ]. The common reason for donor rejection during LDLT donor screening is an ABO mismatch [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

ABO incompatible living donor liver transplant with antibody titer of 1:4: First case report from Pakistan

Dogar

Ullah

Bilal

et al. 2022

Annals of Medicine &Amp; Surgery

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“…The donor was selected according to our selection criteria. 8 The right lobe without middle hepatic vein was transplanted. Graft weight was 480gm, having a single right hepatic duct, right portal vein, and right hepatic vein.…”

Section: Introductionmentioning

confidence: 99%

Experience of our First-Ever Living Donor Liver Transplantation In Hiv-Positive Patient-Report From Developing Country with Literature Review

Dogar¹,

Ullah²,

Raza³

et al. 2021

PJMHS

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Human Immunodeficiency Virus (HIV) is one of the gravest health challenges worldwide in the present era as it has been for the past 4 decades. HIV has always been a sort of stigma and most clinicians are reluctant to perform liver transplantation for chronic liver disease patients with HIV co-infection. Patients with CD4+ cell count >100/ml along with suppressed mRNA levels on PCR, stable HAART regimen, and absence of any AIDS-specific illness or opportunistic infectionsare the requirements for selecting HIV-positive recipients for liver transplantation. We report the first living donor liver transplant in an HIV-positive recipient in a developing country. Here are the details of the case. Keywords: HIV, living donor, Liver transplantation, developing country

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Frequency and Outcome of Hepatic Arterial Thrombosis in Recipients of Living Donor Liver Transplantation

Abstract: Objective: To determine the frequency, risk factors, and management of hepatic arterial thrombosis (HAT) in recipients of living donor living transplantation.

Cited by 7 publications

References 18 publications

Splenic artery transposition for hepatic arterial supply in living donor liver transplantation

Splenic artery transposition for hepatic arterial supply in living donor liver transplantation

ABO incompatible living donor liver transplant with antibody titer of 1:4: First case report from Pakistan

Experience of our First-Ever Living Donor Liver Transplantation In Hiv-Positive Patient-Report From Developing Country with Literature Review

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