Freezing of gait in patients with advanced Parkinson's disease

Giladi, Nir; Treves, T. A.; Simon, Ely S.; Shabtai, H.; Orlov, Yivgeny; Kandinov, Boris; Paleacu, Diana; Korczyn, Amos D.

doi:10.1007/s007020170096

Cited by 342 publications

(287 citation statements)

References 17 publications

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“…Our study found that around 47% of patients with PD that attended a Brazilian specialized movement disorder clinic reported FOG. Other previous studies reported variable findings, and this large variability may be probably explained by methodological differences such as the criteria to identify FOG and by the clinical characteristics of the sample evaluated [14][15][16] . Our patients with PD and FOG had a longer disease duration compared to patients without it, which is consonant with previous studies showing a strong association between FOG and the duration and severity of the disease 4,17 .…”

Section: Discussionmentioning

confidence: 83%

Validity of the Brazilian version of the freezing of gait questionnaire

Baggio

Curtarelli

Rodrigues

et al. 2012

Arq. Neuro-Psiquiatr.

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OBJECTIVE: To validate the freezing of gait questionnaire (FOG-Q) for a Brazilian population of Parkinson's disease (PD) patients. METHODS: One hundred and seven patients with a diagnosis of PD were evaluated by shortened UPDRS motor scale (sUPDRm), Hoehn and Yahr (HY), Schwab and England scale (SE), Berg balance scale (BBS), falls efficacy scale international (FES-I), gait and balance scale (GABS), and the FOG-Q Brazilian version. RESULTS: 47.7% of PD patients had FOG episodes; this group had worse scores on sUPDRSm, FOGQ, FES-I, BBS, GABS and FOG item of UPDRS when compared to the PD group without FOG. The internal consistency was 0.86, intra-rater 0.82 and inter-rater 0.78. The FOG-Q Brazilian version was significantly correlated with items related to gait and balance. The ROC curve was 0.94, the sensitivity was 0.90and specificity was 0.92. CONCLUSION: Our study suggests that the FOG-Q Brazilian version is a reliable and valid instrument for assessing FOG in PD patients.

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Section: Discussionmentioning

confidence: 83%

Validity of the Brazilian version of the freezing of gait questionnaire

Baggio

Curtarelli

Rodrigues

et al. 2012

Arq. Neuro-Psiquiatr.

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“…FOG appears as a transient episode in which the individual is unable to generate a step. Importantly, this phenomenon is not present in all individuals with PD (Bloem, Hausdorff, Visser, & Giladi, 2004;Giladi et al, 2001). There have been many hypotheses that have tried to explain this phenomenon, including one which suggested that FOG may have 3 perceptual origins (Almeida & Lebold, 2010).…”

Section: List Of Tablesmentioning

confidence: 96%

Dopaminergic contributions to distance estimation in Parkinson's disease: A sensory-perceptual deficit?

2013

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“…A feeling of being glued to the floor is typically expressed. FOG can be quite disabling, impairing function, health-related quality of life, mobility, and independence (Gray & Hildebrand, 2000;Giladi et al, 2001). Because of its episodic nature, patients with FOG have an increased risk for falls, nursing home admission, and mortality (Gray & Hildebrand, 2000).…”

Section: Freezing Of Gaitmentioning

confidence: 99%

Gait dynamics, fractals and falls: Finding meaning in the stride-to-stride fluctuations of human walking

Hausdorff

2007

Human Movement Science

707

594

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Until recently, quantitative studies of walking have typically focused on properties of a typical or average stride, ignoring the stride-to-stride fluctuations and considering these fluctuations to be noise. Work over the past two decades has demonstrated, however, that the alleged noise actually conveys important information. The magnitude of the stride-to-stride fluctuations and their changes over time during a walk -gait dynamics -may be useful in understanding the physiology of gait, in quantifying age-related and pathologic alterations in the locomotor control system, and in augmenting objective measurement of mobility and functional status Indeed, alterations in gait dynamics may help to determine disease severity, medication utility, and fall risk, and to objectively document improvements in response to therapeutic interventions, above and beyond what can be gleaned from measures based on the average, typical stride. This review discusses support for the idea that gait dynamics has meaning and may be useful in providing insight into the neural control of locomtion and for enhancing functional assessment of aging, chronic disease, and their impact on mobility.

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Freezing of gait in patients with advanced Parkinson's disease

Abstract: Introduction

Cited by 342 publications

References 17 publications

Validity of the Brazilian version of the freezing of gait questionnaire

Validity of the Brazilian version of the freezing of gait questionnaire

Dopaminergic contributions to distance estimation in Parkinson's disease: A sensory-perceptual deficit?

Gait dynamics, fractals and falls: Finding meaning in the stride-to-stride fluctuations of human walking

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